| Place | Time | Swimmer (Grade) | School | City | State |
| 1 | 4:34.78 | Dagny Knutson (11) | Minot High School | Minot | ND |
| 2 | 4:41.98 | Amber McDermott (10) | H. M. Jackson High School | Mill Creek | WA |
| 3 | 4:42.46 | Haley Anderson (12) | Granite Bay High School | Granite Bay | CA |
| 4 | 4:43.96 | Jasmine Tosky (9 ) | Palo Alto High School | Palo Alto | CA |
| 5 | 4:44.29 | Siena DeVenuto (11) | Pine Crest School | Fort Lauderdale | FL |
| 6 | 4:44.39 | Elizabeth Beisel (11) | North Kingstown High School | North Kingstown | RI |
| 7 | 4:44.90 | Catherine Breed (10) | Amador Valley High School | Pleasanton | CA |
| 8 | 4:46.28 | Allison Arnold (11) | Highland Park High School | Dallas | TX |
| 9 | 4:46.57 | Erin Foster (10) | The Woodlands High School | The Woodlands | TX |
| 9 | 4:46.57 | Lynette Lim (11) | Palm Springs High School | Palm Springs | CA |
| 11 | 4:46.66 | Adrienne Bicek (12) | Downers Grove North High School | Downers Grove | IL |
| 12 | 4:46.78 | Rachel Naurath (11) | The Collegiate School | Richmond | VA |
| 13 | 4:47.59 | Stephanie Peacock (11) | Bishop Verot Catholic School | Fort Myers | FL |
| 14 | 4:47.81 | Caitlin Hamilton (12) | Normal Community High School | Normal | IL |
| 15 | 4:48.06 | Corinne Showalter (12) | Riverview High School | Sarasota | FL |
| 16 | 4:48.13 | Angela Severn (12) | Souderton Area High School | Souderton | PA |
| 17 | 4:48.60 | Aja Van Hout (10) | Madison East High School | Madison | WI |
| 18 | 4:48.71 | Kelsey Gaid (12) | Pope High School | Marietta | GA |
| 19 | 4:48.88 | Kelsey Hall (12) | West Hills High School | Santee | CA |
| 20 | 4:48.90 | Sommers Creed (10) | Mill Creek High School | Hoschton | GA |
| 21 | 4:48.91 | Maureen McLaine (12) | Plano West Senior High School | Plano | TX |
| 22 | 4:49.13 | Monica Dornick (10) | Carlsbad High School | Carlsbad | CA |
| 23 | 4:49.35 | Tristin Baxter (11) | Clovis West High School | Fresno | CA |
| 24 | 4:50.14 | Rachael Burnett (12) | Annandale High School | Annandale | VA |
| 25 | 4:50.35 | Delise Batiza (10) | California High School | San Ramon | CA |
| 26 | 4:50.55 | Kiera Janzen (10) | Cretin-Derham Hall High School | St. Paul | MN |
| 27 | 4:50.78 | Silken Jones (10) | San Clemente High School | San Clemente | CA |
| 28 | 4:50.84 | Taylor Nanfria (10) | San Ramon Valley High School | Danville | CA |
| 29 | 4:50.86 | Rheanna Vaughn (11) | Aliso Niguel High School | Aliso Viejo | CA |
| 30 | 4:50.87 | Sarah Andrews (12) | Centerville High School | Centerville | OH |
| 31 | 4:50.97 | Jaime Malandra (12) | Parkland High School | Allentown | PA |
| 32 | 4:51.04 | Allison Brown (9 ) | San Ramon Valley High School | Danville | CA |
| 33 | 4:51.38 | Claire Singley (11) | Southlake Carroll High School | Southlake | TX |
| 34 | 4:51.61 | Hillary Petersen (11) | Buchholz High School | Gainesville | FL |
| 35 | 4:51.67 | Sarah Goss (11) | Ravenwood High School | Brentwood | TN |
| 36 | 4:51.68 | Kelly Ann Baird (11) | West Davidson High School | Lexington | NC |
| 37 | 4:52.17 | Jessica Heim (11) | Horizon Junior/Senior High School | San Diego | CA |
| 38 | 4:52.41 | Casey Ridge (12) | St. Ursula Academy | Cincinnati | OH |
| 39 | 4:52.70 | Chelsea Wild (12) | Laguna Beach High School | Laguna Beach | CA |
| 40 | 4:52.87 | Brittany Walsh (11) | Muskego High School | Muskego | WI |
| 41 | 4:52.89 | Elizabeth Nelson (12) | The Woodlands College Park High School | The Woodlands | TX |
| 42 | 4:52.97 | Amy Modglin (12) | Fort Myers High School | Ft. Myers | FL |
| 43 | 4:53.04 | Kathryn Campbell (9 ) | La Canada High School | La Canada | CA |
| 44 | 4:53.06 | Erika Deardorf (12) | The Woodlands High School | The Woodlands | TX |
| 45 | 4:53.25 | Jordan Bowen (12) | Stillwater High School | Stillwater | MN |
| 46 | 4:53.49 | Bonnie Brandon (9 ) | Cherry Creek High School | Greenwood Village | CO |
| 47 | 4:53.54 | Lauren Weis (12) | Cretin-Derham Hall High School | St. Paul | MN |
| 48 | 4:53.73 | Megan Rankin (9 ) | University High School | Irvine | CA |
| 49 | 4:53.75 | Melanie Margalis (11) | Countryside High School | Clearwater | FL |
| 50 | 4:53.95 | Lauren Jordan (10) | Carmel High School | Carmel | IN |
| 51 | 4:54.18 | Kelsey Hojan-Clark (10) | Brookfield Academy | Brookfield | WI |
| 52 | 4:54.21 | Meredith King (12) | duPont Manual High School | Louisville | KY |
| 53 | 4:54.26 | Abigail Chin (10) | Upper Arlington High School | Upper Arlington | OH |
| 54 | 4:54.32 | Kate Woolbright (10) | East Ridge High School | Clermont | FL |
| 55 | 4:54.58 | Megan Rossi (10) | Clearwater High School | Clearwater | FL |
| 56 | 4:54.65 | Katie Delaney (10) | Middleton High School | Middleton | WI |
| 57 | 4:54.85 | Jessica Wolf (9 ) | Muskego High School | Muskego | WI |
| 58 | 4:54.89 | Kelsey Cummings (10) | El Segundo High School | El Segundo | CA |
| 59 | 4:54.95 | Lauren Gray (10) | Hidden Valley High School | Roanoke | VA |
| 60 | 4:54.96 | Cha Cha Bugatti (10) | Riverview High School | Sarasota | FL |
| 61 | 4:55.08 | Megan Gallagher (10) | McCutcheon High School | Lafayette | IN |
| 62 | 4:55.19 | Rachel Godfred (12) | Mercer Island High School | Mercer Island | WA |
| 63 | 4:55.25 | Kelly Tannhauser (11) | Juanita High School | Kirkland | WA |
| 64 | 4:55.33 | Taylor Munk (11) | San Ramon Valley High School | Danville | CA |
| 65 | 4:55.36 | Erin Sosdian (11) | The Woodlands College Park High School | The Woodlands | TX |
| 66 | 4:55.56 | Kacie Ciampoli (10) | Germantown Academy | Ft. Washington | PA |
| 67 | 4:55.65 | Eleanor Prewitt-Thomas (12) | Blue Springs High School | Blue Springs | MO |
| 68 | 4:55.69 | Caroline Myers (11) | Palm Harbor University High School | Palm Harbor | FL |
| 69 | 4:55.76 | Danielle Smith (11) | Boca Raton High School | Boca Raton | FL |
| 70 | 4:55.77 | Sloane Pitman (12) | The Baylor School | Chattanooga | TN |
| 71 | 4:55.90 | Caylyn Tate (12) | Potomac Falls High School | Sterling | VA |
| 72 | 4:55.94 | Andrea Staub (11) | Delone Catholic High School | McSherrystown | PA |
| 73 | 4:56.15 | Damaris Iriondo (10) | St Thomas Aquinas High School | Fort Lauderdale | FL |
| 74 | 4:56.18 | Kristyn Fulcher (11) | Upper Arlington High School | Upper Arlington | OH |
| 75 | 4:56.21 | Fiona Majeau (10) | Garfield High School | Seattle | WA |
| 75 | 4:56.21 | Kasey Morris (11) | Oscar Smith High School | Chesapeake | VA |
| 77 | 4:56.25 | Olivia Kabacinski (9 ) | Chesterton High School | Chesterton | IN |
| 77 | 4:56.25 | Alyssa Swanson (12) | Regis Jesuit High School | Aurora | CO |
| 79 | 4:56.38 | Maria Watkins (11) | Winston Churchill High School | Potomac | MD |
| 80 | 4:56.39 | Molly Hazelbaker (9 ) | Turpin High School | Cincinnati | OH |
| 81 | 4:56.52 | Laurin Williams (11) | Shorewood High School | Shoreline | WA |
| 82 | 4:56.57 | Sydney Stinner (9 ) | Allentown Central Catholic High School | Allentown | PA |
| 83 | 4:56.65 | Hayley Edwards (12) | Woodstown High School | Woodstown | NJ |
| 84 | 4:56.72 | Kaia Simmons (12) | Moses Brown School | Providence | RI |
| 84 | 4:56.72 | Samantha Zuch (11) | Napoleon High School | Napoleon | OH |
| 86 | 4:56.82 | Lizzie Justice (11) | The Woodlands High School | The Woodlands | TX |
| 87 | 4:56.86 | Allie Evans (12) | St. Petersburg High School | St. Petersburg | FL |
| 88 | 4:56.88 | Stephanie Eisenring (12) | Pine Crest School | Fort Lauderdale | FL |
| 89 | 4:56.95 | Hayley Shillington (11) | Oaks Christian High School | Westlake Village | CA |
| 90 | 4:57.00 | Kelsey Herbst (12) | McDowell High School | Erie | PA |
| 90 | 4:57.00 | Sterling Wine (12) | Lake Highland Preparatory School | Orlando | FL |
| 92 | 4:57.05 | Audrey Lawson (12) | Notre Dame Academy | Park Hills | KY |
| 93 | 4:57.09 | Stephanie Martinez (10) | Fort Myers High School | Fort Myers | FL |
| 94 | 4:57.20 | Erica Reifinger (9 ) | Parkland High School | Allentown | PA |
| 95 | 4:57.24 | Alison Moffit (11) | Flower Mound High School | Flower Mound | TX |
| 96 | 4:57.29 | Joan Weaver (12) | Sayville High School | Sayville | NY |
| 97 | 4:57.31 | Breann McDowell (11) | Ursuline Academy | Cincinnati | OH |
| 98 | 4:57.33 | Julia Festa (11) | Great Neck South High School | Great Neck | NY |
| 99 | 4:57.45 | Abby Duckett (9 ) | Palo Alto High School | Palo Alto | CA |
| 100 | 4:57.56 | Claire Loht (10) | Red Land High School | Lewisberry | PA |
| 101 | 4:57.58 | Salena Huang (10) | Irvington High School | Fremont | CA |
| 102 | 4:57.74 | Andrea Ward (11) | Campolindo High School | Moraga | CA |
| 103 | 4:57.84 | Kally Fayhee (12) | Rosary High School | Aurora | IL |
| 103 | 4:57.84 | Kelly Johanson (10) | Mamaroneck High School | Mamaroneck | NY |
| 105 | 4:57.87 | Quincy Christian (11) | Granite Bay High School | Granite Bay | CA |
| 106 | 4:57.93 | Sloan Storie (12) | Corvallis High School | Corvallis | OR |
| 107 | 4:57.96 | Caitlin Connor (12) | Hinsdale Central High School | Hinsdale | IL |
| 108 | 4:58.00 | Kennedy Higdon (11) | Bearden High School | Knoxville | TN |
| 109 | 4:58.09 | Lara Slesnick (11) | LBJ High School | Austin | TX |
| 110 | 4:58.23 | Rachael Dudley (9 ) | Mill Creek High School | Hoschton | GA |
| 111 | 4:58.31 | Karima Chuk (11) | Catalina Foothills High School | Tucson | AZ |
| 112 | 4:58.35 | Amelia Marsh (11) | Okemos High School | Okemos | MI |
| 113 | 4:58.45 | Tamara Wadgymar (11) | The Bolles School | Jacksonville | FL |
| 114 | 4:58.48 | Greta Reichert (12) | Wildwood Catholic High School | North Wildwood | NJ |
| 115 | 4:58.53 | Kristen Redmond (12) | Centennial High School | Roswell | GA |
| 116 | 4:58.64 | Jacqueline Levere (10) | Saint Francis High School | Mountain View | CA |
| 117 | 4:58.65 | Katie Nemann (11) | Turpin High School | Cincinnati | OH |
| 118 | 4:58.72 | Rocky Raybon (11) | Riverview High School | Sarasota | FL |
| 119 | 4:58.73 | Courtney Sheehan (10) | Waukesha South High School | Waukesha | WI |
| 120 | 4:58.74 | Bridget Casey (10) | Germantown Academy | Ft. Washington | PA |
| 121 | 4:58.84 | Becky Flora (12) | McDonogh School | Owings Mills | MD |
| 122 | 4:58.86 | Lexy Troup (9 ) | Monte Vista High School | Danville | CA |
| 123 | 4:58.88 | Briana Meyer (12) | Ballard High School | Seattle | WA |
| 124 | 4:58.89 | Molly Dengler (12) | New Albany High School | New Albany | OH |
| 125 | 4:58.94 | Laura Loughran (11) | Peddie School | Hightstown | NJ |
| 126 | 4:58.95 | Hailey White (11) | Duluth High School | Duluth | GA |
| 127 | 4:59.02 | Elizabeth Kleiner (10) | Lakeville North High School | Lakeville | MN |
| 128 | 4:59.11 | Allie Davis (9 ) | Windsor High School | Windsor | CA |
| 128 | 4:59.11 | Sarah Williford (9 ) | Lassiter High School | Marietta | GA |
| 130 | 4:59.15 | Lauren Baisden (12) | West Chester Henderson High School | West Chester | PA |