| Place | Time | Swimmer (Grade) | School | City | State |
| 1 | :22.40 | Margo Geer (11) | Fairbanks High School | Milford Center | OH |
| 2 | :22.53 | Sloane Pitman (12) | The Baylor School | Chattanooga | TN |
| 3 | :22.55 | Maddy Schaefer (10) | Saint Francis High School | Mountain View | CA |
| 4 | :22.61 | Kasey Carlson (11) | Las Lomas High School | Walnut Creek | CA |
| 5 | :22.62 | Emily Bos (11) | Holland High School | Holland | MI |
| 6 | :22.73 | Hannah Bowen (10) | Stillwater High School | Stillwater | MN |
| 7 | :22.80 | Gretchen Jaques (10) | Glendora High School | Glendora | CA |
| 8 | :22.83 | Paige Whitmire (12) | Souderton Area High School | Souderton | PA |
| 9 | :22.87 | Lauren Perdue (12) | J. H. Rose High School | Greenville | NC |
| 10 | :22.89 | Gracie Finnegan (11) | Bishop Watterson High School | Columbus | OH |
| 10 | :22.89 | Kathryn Murphy (11) | Marin Catholic High School | Kentfield | CA |
| 12 | :22.94 | Cynthia Fascella (11) | Fountain Valley High School | Fountain Valley | CA |
| 13 | :22.99 | Emma Drysdale (12) | Monta Vista High School | Cupertino | CA |
| 14 | :23.04 | Samantha Tucker (11) | Westlake High School | Austin | TX |
| 15 | :23.05 | Haley Krakoski (11) | Xavier College Preparatory | Phoenix | AZ |
| 16 | :23.07 | Kaitlin Frehling (11) | Seminole High School | Seminole | FL |
| 17 | :23.10 | Ruby Martin (12) | Madison East High School | Madison | WI |
| 17 | :23.10 | Erin Reisinger (11) | Walton High School | Marietta | GA |
| 19 | :23.11 | Sara Delay (11) | Northgate High School | Walnut Creek | CA |
| 19 | :23.11 | Kathryn Eckhart (9 ) | Cypress Creek High School | Houston | TX |
| 21 | :23.12 | Kelsey Amundsen (12) | The Woodlands High School | The Woodlands | TX |
| 22 | :23.14 | Kate McNeilis (11) | Dublin Scioto High School | Dublin | OH |
| 22 | :23.14 | Molly Osterhage (11) | Centerville High School | Centerville | OH |
| 24 | :23.16 | Skylar Smith (10) | Foster High School | Richmond | TX |
| 25 | :23.18 | Stephanie Eisenring (12) | Pine Crest School | Fort Lauderdale | FL |
| 26 | :23.22 | Mikelle Masciantonio (11) | Emmaus High School | Emmaus | PA |
| 27 | :23.23 | Megan Detro (12) | Carmel High School | Carmel | IN |
| 28 | :23.24 | Katherine Carl (12) | Bloomfield Hills Lahser High School | Bloomfield Hills | MI |
| 28 | :23.24 | Abigail Staats (12) | Winona High School | Winona | MN |
| 28 | :23.24 | Alexandra Whitford (11) | Bella Vista High School | Fair Oaks | CA |
| 31 | :23.29 | Anna Dobben (12) | Homewood-Flossmoor High School | Flossmoor | IL |
| 31 | :23.29 | Lauren Nichols (12) | Seaholm High School | Birmingham | MI |
| 31 | :23.29 | Natilee Ruiz (9 ) | Othello High School | Othello | WA |
| 31 | :23.29 | Kayla Smith (12) | Madison Memorial High School | Madison | WI |
| 35 | :23.30 | Patricia Leeson (11) | Liberty High School | Bethlehem | PA |
| 36 | :23.34 | Dagny Knutson (11) | Minot High School | Minot | ND |
| 37 | :23.35 | Katherine Zander (10) | Orange Park High School | Orange Park | FL |
| 38 | :23.36 | Samantha Moffitt (10) | Cedar Crest High School | Lebanon | PA |
| 38 | :23.36 | Mary Moser (11) | Wyomissing Area High School | Wyomissing | PA |
| 40 | :23.37 | Krissie Brandenburg (11) | Beechwood High School | Fort Mitchell | KY |
| 40 | :23.37 | Katie Nolan (12) | Hershey High School | Hershey | PA |
| 42 | :23.40 | Erica Dittmer (11) | Klein High School | Klein | TX |
| 42 | :23.40 | Amanda Kendall (12) | Robinson Secondary School | Fairfax | VA |
| 42 | :23.40 | Kaila Lee (11) | Willamette High School | Eugene | OR |
| 45 | :23.42 | Kaley Dodson (11) | Los Alamitos High School | Los Alamitos | CA |
| 46 | :23.43 | Carly Mercer (11) | Hamilton Southeastern High School | Fishers | IN |
| 47 | :23.44 | Ellie Johnson (12) | Mountain Ridge High School | Glendale | AZ |
| 47 | :23.44 | Mallory Morrell (12) | Rush Henrietta High School | Henrietta | NY |
| 49 | :23.45 | Megan Fonteno (10) | The Bolles School | Jacksonville | FL |
| 50 | :23.46 | Lauren Weaver (11) | Colerain High School | Cincinnati | OH |
| 51 | :23.47 | Bonnie Brandon (9 ) | Cherry Creek High School | Greenwood Village | CO |
| 51 | :23.47 | Kara Savegnago (12) | Rosary High School | Aurora | IL |
| 53 | :23.48 | Tori Bagan (10) | Homestead High School | Fort Wayne | IN |
| 53 | :23.48 | Lauren Harrington (10) | St. Mary's Episcopal School | Memphis | TN |
| 55 | :23.49 | Susanne Gingher (10) | State College High School | State College | PA |
| 55 | :23.49 | Kate Klippert (11) | Newport Harbor High School | Newport Beach | CA |
| 55 | :23.49 | Dana Nessler (11) | The Bolles School | Jacksonville | FL |
| 58 | :23.51 | Allison Hendren (12) | Leesville Road High School | Raleigh | NC |
| 58 | :23.51 | Emily Lloyd (11) | Severna Park High School | Severna Park | MD |
| 58 | :23.51 | Julianne McNamee (12) | Dublin Jerome High School | Dublin | OH |
| 61 | :23.52 | Kait Flederbach (11) | Westfield High School | Westfield | IN |
| 61 | :23.52 | Mary Griffith (9 ) | Tokay High School | Lodi | CA |
| 61 | :23.52 | Lauren Massey (12) | North Central High School | Indianapolis | IN |
| 64 | :23.54 | Alexandra Bilunas (10) | Duchesne Academy | Omaha | NE |
| 64 | :23.54 | Katie Howard (11) | Sacred Heart Prepararory | Atherton | CA |
| 64 | :23.54 | Katelyn Miller (10) | Hershey High School | Hershey | PA |
| 67 | :23.55 | Alana Pazevic (11) | H. M. Jackson High School | Mill Creek | WA |
| 67 | :23.55 | M.E. Randall (11) | College Park High School | Pleasant Hill | CA |
| 69 | :23.58 | Kelly Hagerty (11) | Glenbrook South High School | Glenview | IL |
| 70 | :23.59 | Tess Behrens (11) | Maple Grove Senior High | Maple Grove | MN |
| 70 | :23.59 | Katelin Scarsella (12) | Westlake High School | Austin | TX |
| 72 | :23.60 | Margaret Anderson (12) | H.B. Plant High School | Tampa | FL |
| 72 | :23.60 | Missy Doll (11) | Souderton Area High School | Souderton | PA |
| 72 | :23.60 | Chelsey Eberwein (12) | The Woodlands High School | The Woodlands | TX |
| 72 | :23.60 | Ashley McAteer (12) | Penn-Trafford High School | Harrison City | PA |
| 76 | :23.62 | Rachel Cruze (11) | Hardin Valley Academy | Knoxville | TN |
| 76 | :23.62 | Kristen Wilson (11) | Paul Laurence Dunbar High School | Lexington | KY |
| 78 | :23.63 | Erin Caflisch (11) | Mayo High School | Rochester | MN |
| 78 | :23.63 | Evann Heidersbach (12) | Elyria Catholic High School | Elyria | OH |
| 78 | :23.63 | Mary Van Metre (11) | Edina High School | Edina | MN |
| 81 | :23.64 | Elizabeth Hall (12) | Chantilly High School | Chantilly | VA |
| 82 | :23.66 | Melissa Cooper (11) | American Heritage School | Plantation | FL |
| 82 | :23.66 | Kayla Hammerberg (10) | Upper Arlington High School | Upper Arlington | OH |
| 82 | :23.66 | Lindsay Parrish (12) | Santa Barbara High School | Santa Barbara | CA |
| 82 | :23.66 | Brienne Ryan (12) | Cornwall Central High School | New Windsor | NY |
| 82 | :23.66 | Samantha Wierzbicki (11) | Wilson High School | West Lawn | PA |
| 87 | :23.67 | Laurel Chaney (12) | Bearden High School | Knoxville | TN |
| 87 | :23.67 | Kara Stranski (11) | St. Mary's Academy | Portland | OR |
| 89 | :23.68 | Andrea Grant (10) | Walnut High School | Walnut | CA |
| 89 | :23.68 | Sara Li (11) | Longmeadow High School | Longmeadow | MA |
| 89 | :23.68 | Mallory Przybylinski (12) | Chesterton High School | Chesterton | IN |
| 89 | :23.68 | Danielle Yoho (12) | Clements High School | Sugar Land | TX |
| 93 | :23.69 | Lilly Marrow (11) | Houston Stratford High School | Houston | TX |
| 94 | :23.70 | Sarah Denninghoff (11) | Sabino High School | Tucson | AZ |
| 94 | :23.70 | Calley Parham (12) | Monterey High School | Lubbock | TX |
| 96 | :23.71 | Jesse Bergman (11) | Homestead High School | Cupertino | CA |
| 97 | :23.72 | Ginny Grams (10) | Spruce Creek High School | Port Orange | FL |
| 98 | :23.73 | Treasa Ring (12) | Roseville Area High School | Roseville | MN |
| 98 | :23.73 | Heather Savage (12) | Canandaigua Academy | Canandaigua | NY |
| 98 | :23.73 | Katie Tomkinson (12) | Carlsbad High School | Carlsbad | CA |
| 101 | :23.74 | Meredith Cavalier (12) | Brooke Point High School | Stafford | VA |
| 101 | :23.74 | Nadia El-Hamdi (10) | James Bowie High School | Austin | TX |
| 101 | :23.74 | Shelley Perkins (12) | Chatfield Senior High School | Littleton | CO |
| 104 | :23.75 | Caroline McElhany (12) | Friendswood High School | Friendswood | TX |
| 104 | :23.75 | Kelsie Schooley (12) | Holt High School | Holt | MI |
| 104 | :23.75 | Kelsey Vermeer (12) | Rockford High School | Rockford | MI |
| 107 | :23.76 | Mary Bank (11) | Ryle High School | Union | KY |
| 107 | :23.76 | Marissa Konicke (10) | Plano Senior High School | Plano | TX |
| 107 | :23.76 | Jackie Rzymek (12) | McDowell High School | Erie | PA |
| 107 | :23.76 | Lauren Scott (12) | Starr's Mill High School | Fayetteville | GA |
| 111 | :23.77 | Jessica Graber (11) | Walton High School | Marietta | GA |
| 111 | :23.77 | Kelsey Krauss (12) | St. Petersburg Catholic High | St. Petersburg | FL |
| 111 | :23.77 | Taylor Straub (10) | Wilson High School | West Lawn | PA |
| 111 | :23.77 | Lauryl Williams (9 ) | Dorman High School | Roebuck | SC |
| 115 | :23.78 | Amber Cratsenberg (9 ) | Thomas Jefferson High School | Auburn | WA |
| 115 | :23.78 | Zoe Mattingly (9 ) | Zionsville Community High School | Zionsville | IN |
| 115 | :23.78 | Patricia Nelson (11) | Fort Collins High School | Fort Collins | CO |
| 118 | :23.79 | Brittany Fozkos (11) | Chesterton High School | Chesterton | IN |
| 119 | :23.81 | Madeline Armitage (12) | Upper Arlington High School | Upper Arlington | OH |
| 119 | :23.81 | Sarah Liang (10) | Palo Alto High School | Palo Alto | CA |
| 121 | :23.82 | Sabrina Cochrane (11) | San Marin High School | Novato | CA |
| 121 | :23.82 | Maddy Dalcamo (11) | Olathe Northwest High School | Olathe | KS |
| 121 | :23.82 | Meghann McGoldrick (12) | Churchill High School | San Antonio | TX |
| 121 | :23.82 | Melissa McMahon (11) | Lakeville South High School | Lakeville | MN |
| 121 | :23.82 | Alyssa Tran (12) | Esperanza High School | Anaheim | CA |
| 126 | :23.83 | Chardonnay Biter-Mundt (12) | Vintage High School | Napa | CA |
| 126 | :23.83 | Allie Bollella (12) | Palo Alto High School | Palo Alto | CA |
| 126 | :23.83 | Sophie Pilhofer (12) | Visitation High School | Mendota Heights | MN |
| 129 | :23.84 | Ashley Corriveau (12) | Lapeer East High School | Lapeer | MI |
| 130 | :23.85 | Jenna Gregoire (11) | Rampart High School | Colorado Springs | CO |
| 130 | :23.85 | Sierra Robbins (10) | Miramonte High School | Orinda | CA |
| 130 | :23.85 | Laura Slater (11) | Redwood High School | Larkspur | CA |
| 133 | :23.86 | Holly Berenotto (12) | Egg Harbor Township High School | Egg Harbor Twp. | NJ |
| 133 | :23.86 | Samantha Bosma (10) | Lassiter High School | Marietta | GA |
| 133 | :23.86 | Kelsey Engel (11) | El Toro High School | Lake Forest | CA |
| 133 | :23.86 | Mamie Hobbs (12) | Champaign Central High School | Champaign | IL |
| 133 | :23.86 | Ivy Martin (10) | Madison East High School | Madison | WI |