| Place | Time | Name (Yr) | School | City | State |
| 1 | :22.24 | Maddy Schaefer (11) | Saint Francis High School | Mountain View | CA |
| 2 | :22.35 | Margo Geer (12) | Fairbanks High School | Milford Center | OH |
| 3 | :22.49 | Missy Franklin (9 ) | Regis Jesuit High School | Aurora | CO |
| 4 | :22.70 | Kasey Carlson (12) | Las Lomas High School | Walnut Creek | CA |
| 5 | :22.74 | Hannah Bowen (11) | Stillwater Area High School | Stillwater | MN |
| 6 | :22.96 | Kathryn Murphy (12) | Marin Catholic High School | Kentfield | CA |
| 7 | :22.97 | Kristen Vredeveld (9 ) | The Baylor School | Chattanooga | TN |
| 8 | :22.98 | Sara Delay (12) | Northgate High School | Walnut Creek | CA |
| 9 | :23.10 | Emily Bos (12) | Holland High School | Holland | MI |
| 10 | :23.11 | Mary Hanson (12) | Immanuel Christian School | Ridgecrest | CA |
| 11 | :23.13 | Kait Flederbach (12) | Westfield High School | Westfield | IN |
| 12 | :23.14 | Kaylin Bing (11) | Roseburg High School | Roseburg | OR |
| 13 | :23.16 | Gracie Finnegan (12) | Bishop Watterson High School | Columbus | OH |
| 13 | :23.16 | Emily Lloyd (12) | Severna Park High School | Severna Park | MD |
| 15 | :23.17 | Rachel Dixon (12) | Las Cruces High School | Las Cruces | NM |
| 15 | :23.17 | Dagny Knutson (12) | Minot High School | Minot | ND |
| 17 | :23.18 | Maddie Locus (11) | Dulles High School | Sugar Land | TX |
| 17 | :23.18 | Mary Moser (12) | Wyomissing Area High School | Wyomissing | PA |
| 19 | :23.22 | Courtney Wilde (11) | Laguna Hills High School | Laguna Hills | CA |
| 20 | :23.26 | Kaila N. Lee (12) | Willamette High School | Eugene | OR |
| 21 | :23.27 | Carly Mercer (12) | Hamilton Southeastern High School | Fishers | IN |
| 22 | :23.31 | Erica Dittmer (12) | Klein High School | Klein | TX |
| 23 | :23.33 | Kathryn Eckhart (10) | Cypress Creek High School | Houston | TX |
| 23 | :23.33 | Cindy Tran (12) | Edison High School | Huntington Beach | CA |
| 25 | :23.34 | Kaitlin Frehling (12) | Seminole High School | Seminole | FL |
| 25 | :23.34 | Ellen Lobb (12) | Clear Lake High School | Houston | TX |
| 27 | :23.38 | Carolyn Fittin (11) | The Peddie School | Hightstown | NJ |
| 27 | :23.38 | Linnea Mack (9 ) | Pioneer High School | San Jose | CA |
| 29 | :23.39 | Sabrina Benson (11) | Broughton High School | Raleigh | NC |
| 30 | :23.41 | Jesse Bergman (12) | Homestead High School | Cupertino | CA |
| 31 | :23.43 | Julia Ama (10) | Gunn High School | Palo Alto | CA |
| 31 | :23.43 | Kelli Benjamin (11) | Gilbert High School | Gilbert | AZ |
| 31 | :23.43 | Jessica Graber (12) | Walton High School | Marietta | GA |
| 31 | :23.43 | Lauren Harrington (11) | St. Mary's Episcopal School | Memphis | TN |
| 35 | :23.45 | Katie Olsen (11) | Desert Vista High School | Phoenix | AZ |
| 36 | :23.46 | Dana Nessler (12) | The Bolles School | Jacksonville | FL |
| 36 | :23.46 | M.E. Randall (12) | College Park High School | Pleasant Hill | CA |
| 38 | :23.47 | Melissa Bates (12) | Mater Dei High School | Santa Ana | CA |
| 38 | :23.47 | Tess Behrens (12) | Maple Grove Senior High School | Maple Grove | MN |
| 40 | :23.48 | Elizabeth Bell (12) | Anna-Jonesboro Community High School | Anna | IL |
| 40 | :23.48 | Andrea Grant (11) | Walnut High School | Walnut | CA |
| 40 | :23.48 | Faith Johnson (10) | High Point Christian Academy | High Point | NC |
| 40 | :23.48 | Jordan Moxley (11) | Cortland Maplewood High School | Cortland | OH |
| 44 | :23.49 | Megan Fonteno (11) | The Bolles School | Jacksonville | FL |
| 44 | :23.49 | Katherine Zander (11) | Orange Park High School | Orange Park | FL |
| 46 | :23.50 | Arden Pitman (11) | The Baylor School | Chattanooga | TN |
| 47 | :23.51 | Katelyn Miller (11) | Hershey High School | Hershey | PA |
| 48 | :23.52 | Kylie Garcia (12) | Rowland High School | Rowland Heights | CA |
| 48 | :23.52 | Alexis Halberstadt (12) | Shanley High School | Fargo | ND |
| 48 | :23.52 | Grace Hoffman (11) | Allen B. Nease High School | Ponte Vedra | FL |
| 51 | :23.53 | Jaynie Pulte (10) | Marian High School | Bloomfield Hills | MI |
| 52 | :23.55 | Anika Apostalon (9 ) | Albuquerque Academy | Albuquerque | NM |
| 52 | :23.55 | Melanie Busch (11) | William Tennent High School | Warminster | PA |
| 52 | :23.55 | Ivy Martin (11) | Madison East High School | Madison | WI |
| 52 | :23.55 | Kristen Wilson (12) | Paul Laurence Dunbar High School | Lexington | KY |
| 56 | :23.56 | Da Yae Choi (10) | Woodbridge High | Irvine | CA |
| 57 | :23.57 | Gretchen Jaques (11) | Glendora High School | Glendora | CA |
| 58 | :23.59 | Lilly Marrow (12) | Stratford High School | Houston | TX |
| 59 | :23.61 | Mikelle Masciantonio (12) | Emmaus High School | Emmaus | PA |
| 60 | :23.62 | Susanne Gingher (11) | State College Area High School | State College | PA |
| 60 | :23.62 | Natalie Rohr (10) | Kettering Fairmont High School | Kettering | OH |
| 60 | :23.62 | Caroline Thomas (11) | Dupont Manual High School | Louisville | KY |
| 63 | :23.63 | Claire Brandt (10) | Greenhill School | Addison | TX |
| 63 | :23.63 | Mikkel-Ane Stipe (12) | La Costa Canyon High School | Carlsbad | CA |
| 63 | :23.63 | Briana Wilford (12) | Catalina Foothills High School | Tucson | AZ |
| 66 | :23.64 | Emily Fogle (12) | Barrington High School | Barrington | IL |
| 66 | :23.64 | Katie Kinnear (10) | Eastlake High School | Sammamish | WA |
| 68 | :23.65 | Krissie Brandenburg (12) | Beechwood High School | Fort Mitchell | KY |
| 69 | :23.67 | Brittany Fozkos (12) | Chesterton High School | Chesterton | IN |
| 69 | :23.67 | Annie Tamblyn (10) | Ann Arbor Huron High School | Ann Arbor | MI |
| 71 | :23.68 | Kara Stranski (12) | St. Mary's Academy | Portland | OR |
| 72 | :23.69 | Rachael Acker (10) | Gunn High School | Palo Alto | CA |
| 73 | :23.70 | Melissa Cooper (12) | American Heritage School | Plantation | FL |
| 74 | :23.72 | Dani Barbiea (11) | Springboro High School | Springboro | OH |
| 74 | :23.72 | Molly Osterhage (12) | Centerville High School | Centerville | OH |
| 76 | :23.73 | Tori Bagan (11) | Homestead High School | Fort Wayne | IN |
| 76 | :23.73 | Suzanne Bessire (11) | Winter Park High School | Winter Park | FL |
| 76 | :23.73 | Harper Bruens (10) | Boca Raton High School | Boca Raton | FL |
| 76 | :23.73 | Britta Sortland (11) | Woodbury High School | Woodbury | MN |
| 76 | :23.73 | Samantha Zuch (12) | Napoleon High School | Napoleon | OH |
| 81 | :23.74 | Michaela Kearney (11) | Mercy High School | Middletown | CT |
| 81 | :23.74 | Marissa Konicke (11) | Plano Senior High School | Plano | TX |
| 81 | :23.74 | Mariah Tharp (12) | Clovis West High School | Fresno | CA |
| 84 | :23.75 | Megan Lydzinski (10) | Montgomery High School | Skillman | NJ |
| 84 | :23.75 | Lauren Weaver (12) | Colerain High School | Cincinnati | OH |
| 86 | :23.76 | Shelby Fortin (12) | Weston High School | Weston | CT |
| 86 | :23.76 | Marissa Murphy (12) | Forest Hills Central High School | Grand Rapids | MI |
| 86 | :23.76 | Amy Wiley (11) | Lakeridge High School | Lake Oswego | OR |
| 86 | :23.76 | Emily Rose Williams (11) | Dos Pueblos High School | Goleta | CA |
| 90 | :23.77 | Emily Baturka (10) | The Episcopal Academy | Newtown Square | PA |
| 91 | :23.78 | Cristina Gonzalez (12) | Portage High School | Portage | IN |
| 91 | :23.78 | Olivia Scott (12) | Rosary High School | Aurora | IL |
| 91 | :23.78 | Rose Thompson (10) | Byron High School | Byron | IL |
| 94 | :23.79 | Missy Doll (12) | Souderton Area High School | Souderton | PA |
| 94 | :23.79 | Emily Neubert (11) | Midway High School | Waco | TX |
| 94 | :23.79 | Courtney Pope (12) | Lockport Township High School | Lockport | IL |
| 94 | :23.79 | Laura Slater (12) | Redwood High School | Corte Madera | CA |
| 94 | :23.79 | Aja Van Hout (11) | Madison East High School | Madison | WI |
| 99 | :23.80 | Chelsea Fong (12) | Monta Vista High School | Cupertino | CA |
| 99 | :23.80 | Silken Jones (11) | San Clemente High School | San Clemente | CA |
| 99 | :23.80 | Kaitlin Kamm (10) | Saint Peter High School | Saint Peter | MN |
| 99 | :23.80 | Lea Koenig (11) | Wausau East High School | Wausau | WI |
| 103 | :23.82 | Kellie Pennington (12) | Monson High School | Monson | MA |
| 103 | :23.82 | Erin Reisinger (12) | Walton High School | Marietta | GA |
| 105 | :23.83 | Rachel Elliott (11) | Gulf Coast High School | Naples | FL |
| 105 | :23.83 | Julianne Phillips (11) | Western Branch High School | Chesapeake | VA |
| 105 | :23.83 | Alexandria Sorensen (10) | The Woodlands High School | The Woodlands | TX |
| 105 | :23.83 | Maddy Urban (12) | New Trier High School | Winnetka | IL |
| 109 | :23.84 | Olivia Carter (10) | Astronaut High School | Titusville | FL |
| 109 | :23.84 | Ginny Grams (11) | Spruce Creek High School | Port Orange | FL |
| 111 | :23.85 | Molly Mucciarone (10) | The Peddie School | Hightstown | NJ |
| 111 | :23.85 | Samantha Wierzbicki (12) | Wilson High School | West Lawn | PA |
| 113 | :23.86 | Kelsey Engel (12) | El Toro High School | Lake Forest | CA |
| 113 | :23.86 | Alli Gillespie (11) | Edison High School | Huntington Beach | CA |
| 113 | :23.86 | Jenna Gregoire (12) | Rampart High School | Colorado Springs | CO |
| 113 | :23.86 | Jane Munro (12) | Evanston Township High School | Evanston | IL |
| 113 | :23.86 | Brittany Robinson (10) | Wawasee High School | Syracuse | IN |
| 118 | :23.87 | Amber Cratsenberg (10) | Thomas Jefferson High School | Auburn | WA |
| 118 | :23.87 | Paige Drazga (11) | South Lyon High School | South Lyon | MI |
| 118 | :23.87 | Victoria Palombit (11) | Coronado High School | Lubbock | TX |
| 118 | :23.87 | Shannon Rauth (9 ) | Downingtown West High School | Downingtown | PA |
| 118 | :23.87 | Chandra Yueh (10) | Breck School | Minneapolis | MN |
| 123 | :23.88 | Chase Kinney (9 ) | Jackson High School | Massillon | OH |
| 123 | :23.88 | Zoe Mattingly (10) | Zionsville Community High School | Zionsville | IN |
| 123 | :23.88 | Evan Swenson (9 ) | Loyola Academy | Wilmette | IL |
| 123 | :23.88 | Chloe Thomas (11) | Souderton Area High School | Souderton | PA |
| 127 | :23.89 | Catherine Galletti (10) | Trinity Preparatory School | Winter Park | FL |
| 127 | :23.89 | Emilie Kaufman (12) | Juanita High School | Kirkland | WA |
| 127 | :23.89 | Carly Marshall (11) | Carmel High School | Carmel | IN |
| 127 | :23.89 | Melanie McDonough (11) | Frisco High School | Frisco | TX |
| 127 | :23.89 | Lauren Mills (11) | Science Hill High School | Johnson City | TN |
| 127 | :23.89 | Julia Pielock (12) | Deerfield Academy | Deerfield | MA |
| 127 | :23.89 | Haley Powell (11) | Lake Norman High School | Mooresville | NC |
| 127 | :23.89 | Maggie Smith (12) | Whitefish Bay High School | Whitefish Bay | WI |