| Place | Time | Swimmer (Yr) | School | City | State |
| 1 | 4:39.17 | Lauren Driscoll (11) | American Heritage School | Plantation | FL |
| 2 | 4:39.96 | Leah Smith (10) | Oakland Catholic High School | Pittsburgh | PA |
| 3 | 4:41.18 | Catherine Breed (12) | Amador Valley High School | Pleasanton | CA |
| 4 | 4:43.04 | Kathryn Campbell (11) | La Canada High School | La Canada - Flintridge | CA |
| 5 | 4:43.78 | Bonnie Brandon (11) | Cherry Creek High School | Greenwood Village | CO |
| 6 | 4:44.20 | Chelsea Chenault (10) | Carondelet High School | Concord | CA |
| 7 | 4:44.29 | Gillian Ryan (9 ) | Kutztown Area High School | Kutztown | PA |
| 8 | 4:45.37 | Megan Rankin (11) | University High School | Irvine | CA |
| 9 | 4:45.69 | Melanie Klaren (12) | Aliso Niguel High School | Aliso Viejo | CA |
| 10 | 4:45.77 | Molly Dubrasky (12) | Estero High School | Estero | FL |
| 11 | 4:46.18 | Jasmine Tosky (11) | Palo Alto High School | Palo Alto | CA |
| 12 | 4:46.28 | Rachel Zilinskas (10) | Germantown Academy | Fort Washington | PA |
| 13 | 4:47.07 | Kelsey Cummings (12) | El Segundo High School | El Segundo | CA |
| 14 | 4:47.57 | Kelsey Leneave (12) | Conroe High School | Conroe | TX |
| 15 | 4:47.69 | Lauren Jordan (12) | Carmel High School | Carmel | IN |
| 16 | 4:48.24 | Allison Brown (11) | San Ramon Valley High School | Danville | CA |
| 17 | 4:48.28 | Jenny Holtzen (11) | Fayetteville High School | Fayetteville | AR |
| 18 | 4:48.39 | Erin Flanigan (12) | Bowie High School | Austin | TX |
| 19 | 4:48.55 | Danielle Valley (10) | Lakewood Ranch High School | Bradenton | FL |
| 20 | 4:48.80 | Kelsey Hojan-Clark (12) | Brookfield Academy | Brookfield | WI |
| 21 | 4:48.84 | Elizabeth Pepper (12) | Walter Johnson High School | Bethesda | MD |
| 22 | 4:48.88 | Nikki Chang (11) | Sonora High School | La Habra | CA |
| 23 | 4:48.93 | Abigail Chin (12) | Upper Arlington High School | Upper Arlington | OH |
| 24 | 4:49.02 | Katie Miller (10) | Akron Firestone High School | Akron | OH |
| 25 | 4:49.40 | Taylor Nanfria (12) | San Ramon Valley High School | Danville | CA |
| 26 | 4:49.50 | Megan Gallagher (12) | McCutcheon High School | Lafayette | IN |
| 27 | 4:49.55 | Taylor Katz (10) | Riverview High School | Sarasota | FL |
| 28 | 4:49.71 | Taylor O'Brien (11) | Emmaus High School | Emmaus | PA |
| 29 | 4:49.85 | Rebecca Stoughton (12) | Peoria Notre Dame High School | Peoria | IL |
| 30 | 4:49.90 | Claire Loht (12) | Red Land High School | Lewisberry | PA |
| 31 | 4:50.29 | Missy Franklin (10) | Regis Jesuit High School | Aurora | CO |
| 32 | 4:50.68 | Cameron McHugh (9 ) | Seven Lakes High School | Katy | TX |
| 33 | 4:51.06 | Ellen Anderson (11) | Gaithersburg High School | Gaithersburg | MD |
| 34 | 4:51.19 | Victoria Mitchell (12) | Cary High School | Cary | NC |
| 35 | 4:51.32 | Lexy Troup (11) | Monte Vista High School | Danville | CA |
| 36 | 4:51.38 | Amanda Barrett (12) | Brighton High School | Salt Lake City | UT |
| 37 | 4:51.52 | Callie Fosburgh (12) | Woodrow Wilson Senior High School | Washington | DC |
| 38 | 4:51.54 | Kacie Ciampoli (12) | Germantown Academy | Fort Washington | PA |
| 39 | 4:51.57 | Brooke Lorentzen (9 ) | Capistrano Valley High School | Mission Viejo | CA |
| 40 | 4:51.63 | Margaret D'Innocenzo (10) | Andover High School | Andover | MA |
| 41 | 4:51.68 | Marissa Brown (11) | San Ramon Valley High School | Danville | CA |
| 42 | 4:51.96 | Erica Reifinger (11) | Parkland High School | Allentown | PA |
| 43 | 4:52.08 | Molly Hazelbaker (11) | Turpin High School | Cincinnati | OH |
| 44 | 4:52.10 | Shelby Hoyt (12) | Forsyth Central High School | Cumming | GA |
| 45 | 4:52.11 | Mikayla Winkler (11) | Vista del Lago High School | Folsom | CA |
| 46 | 4:52.16 | Angie Sawick (12) | Germantown Academy | Fort Washington | PA |
| 47 | 4:52.27 | Zoe Thatcher (9 ) | Mason High School | Mason | OH |
| 48 | 4:52.44 | Kat Simonovic (10) | Mountain View High School | Mesa | AZ |
| 49 | 4:52.47 | Lauren Neidigh (12) | The Bolles School | Jacksonville | FL |
| 50 | 4:52.52 | Sommers Creed (12) | Mill Creek High School | Hoschton | GA |
| 51 | 4:52.65 | Sammy Harrison (11) | Coronado High School | Henderson | NV |
| 52 | 4:52.89 | Rachel Stoehr (11) | Lake Forest High School | Lake Forest | IL |
| 53 | 4:53.16 | Abigail Houck (10) | Fairview High School | Boulder | CO |
| 53 | 4:53.16 | Katie Rogers (12) | Academy Of The Holy Cross | Kensington | MD |
| 55 | 4:53.27 | Megan Cox (11) | Chaparral High School | Scottsdale | AZ |
| 56 | 4:53.85 | Stephanie Marchuk (10) | New Trier High School | Winnetka | IL |
| 57 | 4:53.86 | Caroline Finkbeiner (11) | Trinity High School | Camp Hill | PA |
| 58 | 4:53.93 | Colleen Konetzke (11) | Ronald Reagan High School | San Antonio | TX |
| 59 | 4:53.95 | Kristin VanDeventer (11) | Columbus North High School | Columbus | IN |
| 60 | 4:54.14 | Annika Jonsson (12) | Vista Ridge High School | Cedar Park | TX |
| 61 | 4:54.20 | Ashley Neidigh (10) | The Bolles School | Jacksonville | FL |
| 62 | 4:54.30 | Alexa Davis (11) | Windsor High School | Windsor | CA |
| 63 | 4:54.34 | Paige Matherson (9 ) | San Ramon Valley High School | Danville | CA |
| 64 | 4:54.41 | Aja Vanhout (12) | Madison East High School | Madison | WI |
| 65 | 4:54.43 | Chelsie Miller (11) | Jersey Village High School | Houston | TX |
| 66 | 4:54.45 | Ashley Boyles (10) | Klein Collins High School | Spring | TX |
| 67 | 4:54.52 | Sara Menke (11) | Father Ryan High School | Nashville | TN |
| 68 | 4:54.57 | Jenna Bauer (9 ) | Montgomery High School | Santa Rosa | CA |
| 69 | 4:54.58 | Salena Huang (12) | Irvington High School | Fremont | CA |
| 70 | 4:54.62 | Tara Halsted (10) | Davis Senior High School | Davis | CA |
| 71 | 4:54.70 | Marlee Ehrlich (11) | Cherry Hill High School East | Cherry Hill | NJ |
| 71 | 4:54.70 | Morgan Flynn (10) | Harpeth Hall School | Nashville | TN |
| 73 | 4:54.75 | Charlotte Ruby (11) | Archbishop Mitty High School | San Jose | CA |
| 74 | 4:54.77 | Emmie Ryan (12) | Avon High School | Avon | IN |
| 74 | 4:54.77 | Cecelia Williams (9 ) | Lawton Chiles High School | Tallahassee | FL |
| 76 | 4:54.82 | Jessie James (11) | Corvallis High School | Corvallis | OR |
| 77 | 4:54.84 | Fiona Majeau (12) | Garfield High School | Seattle | WA |
| 78 | 4:54.92 | Ally Loper (12) | Desert Mountain High School | Scottsdale | AZ |
| 79 | 4:54.93 | Nicole Antoniuk (11) | William S. Hart High School | Newhall | CA |
| 80 | 4:55.00 | Meredith Oliver (11) | Robert E. Lee High School | Tyler | TX |
| 81 | 4:55.06 | Riley Spitser (11) | Rancho Bernardo High School | San Diego | CA |
| 82 | 4:55.10 | Kaitlyn Ferrara (10) | St. Ursula Academy | Cincinnati | OH |
| 83 | 4:55.14 | Natalie Amberg (9 ) | Carondelet High School | Concord | CA |
| 84 | 4:55.17 | Camilla Czulada (11) | Wilson High School | West Lawn | PA |
| 85 | 4:55.18 | Emily Zapinski (10) | Southlake Carroll High School | Southlake | TX |
| 86 | 4:55.23 | Amanda Richey (9 ) | Boulder High School | Boulder | CO |
| 87 | 4:55.44 | Marisa Wood (10) | Sartell High School | Sartell | MN |
| 88 | 4:55.45 | Paige Daniel (10) | Manheim Central High School | Manheim | PA |
| 89 | 4:55.66 | Sarah Thompson (12) | Evanston Township High School | Evanston | IL |
| 90 | 4:55.70 | Sophie Weber (11) | Granite Bay High School | Granite Bay | CA |
| 91 | 4:55.71 | Lyndsie Gibson (11) | Southlake Carroll High School | Southlake | TX |
| 92 | 4:55.78 | Damaris Iriondo (12) | St Thomas Aquinas High Schhol | Fort Lauderdale | FL |
| 93 | 4:56.06 | Koryn Ternes (11) | Bowie High School | Austin | TX |
| 94 | 4:56.07 | Madison Jacobi (11) | Harrison High School | Kennesaw | GA |
| 95 | 4:56.11 | Theresa Meyer (12) | Durham School Of The Arts | Durham | NC |
| 96 | 4:56.19 | Bridget Casey (12) | Germantown Academy | Fort Washington | PA |
| 97 | 4:56.34 | Erin Foley (12) | Bishop Feehan High School | Attleboro | MA |
| 98 | 4:56.37 | Sydney King (9 ) | Granville High School | Granville | OH |
| 99 | 4:56.40 | Oriana Wang (11) | Upland High School | Upland | CA |
| 100 | 4:56.45 | Carrie Bencic (10) | Hawken School | Gates Mills | OH |