| Place | Time | Swimmer (Yr) | School | City | State |
| 1 | :22.31 | Maddy Schaefer (12) | Saint Francis High School | Mountain View | CA |
| 2 | :22.41 | Missy Franklin (10) | Regis Jesuit High School | Aurora | CO |
| 3 | :22.45 | Kristen Vredeveld (10) | The Baylor School | Chattanooga | TN |
| 4 | :22.63 | Lauren Harrington (12) | St. Mary's Episcopal School | Memphis | TN |
| 5 | :22.78 | Rachael Acker (11) | Gunn High School | Palo Alto | CA |
| 6 | :22.85 | Madeline Locus (12) | Dulles High School | Sugar Land | TX |
| 7 | :22.94 | Dani Barbiea (12) | Springboro High School | Springboro | OH |
| 8 | :22.99 | Hannah Bowen (12) | Stillwater Area High School | Stillwater | MN |
| 9 | :23.00 | Faith Johnson (11) | High Point Christian Academy | High Point | NC |
| 10 | :23.03 | Bonnie Brandon (11) | Cherry Creek High School | Greenwood Village | CO |
| 11 | :23.09 | Megan Molnar (12) | Auburn High School | Auburn | AL |
| 12 | :23.10 | Heidi Busack (12) | Fergus Falls High School | Fergus Falls | MN |
| 12 | :23.10 | Ivy Martin (12) | Madison East High School | Madison | WI |
| 14 | :23.11 | Julia Ama (11) | Gunn High School | Palo Alto | CA |
| 15 | :23.12 | Olivia Smoliga (10) | Glenbrook South High School | Glenview | IL |
| 16 | :23.16 | Rachel Elliott (12) | Gulf Coast High School | Naples | FL |
| 17 | :23.21 | Chandra Lukes (12) | San Pasqual High School | Escondido | CA |
| 18 | :23.22 | Susanne Gingher (12) | State College Area High School | State College | PA |
| 19 | :23.23 | Carly Marshall (12) | Carmel High School | Carmel | IN |
| 20 | :23.24 | Nikki Barczak (12) | Mercy High School | Farmington Hills | MI |
| 20 | :23.24 | Jaynie Pulte (11) | Marian High School | Bloomfield Hills | MI |
| 22 | :23.26 | Janet Hu (9 ) | Oakton High School | Vienna | VA |
| 23 | :23.27 | Maylin Meisenheimer (11) | King High School | Corpus Christi | TX |
| 24 | :23.29 | Shannon Rauth (10) | Downingtown West High School | Downingtown | PA |
| 25 | :23.31 | Lauren A. Kaufman (12) | Hazen High School | Renton | WA |
| 25 | :23.31 | Victoria Salinas (12) | James Pace High School | Brownsville | TX |
| 27 | :23.33 | Elaina Lanson (12) | Wadsworth City Schools | Wadsworth | OH |
| 27 | :23.33 | Genny Pittman (9 ) | Homewood High School | Homewood | AL |
| 29 | :23.34 | Meaghan Raab (9 ) | Hershey High School | Hershey | PA |
| 30 | :23.35 | Tori Bagan (12) | Homestead High School | Fort Wayne | IN |
| 30 | :23.35 | Olivia Kabacinski (11) | Chesterton High School | Chesterton | IN |
| 32 | :23.38 | Melanie Busch (12) | William Tennent High School | Warminster | PA |
| 32 | :23.38 | Haley Clark (11) | Bryan High School | Bryan | TX |
| 32 | :23.38 | Kaitlyn Dressel (12) | Clay High School | Green Cove Springs | FL |
| 32 | :23.38 | Engel Lindsey (9 ) | Crean Lutheran High School | Irvine | CA |
| 36 | :23.39 | Courtney Wilde (12) | Laguna Hills High School | Laguna Hills | CA |
| 37 | :23.40 | Chase Kinney (10) | Jackson High School | Massillon | OH |
| 38 | :23.41 | Lauren Rhodes (9 ) | Charlotte Catholic High School | Charlotte | NC |
| 39 | :23.42 | Claire Brandt (11) | Greenhill School | Addison | TX |
| 40 | :23.43 | Elizabeth McDonald (11) | Pomperaug High School | Southbury | CT |
| 40 | :23.43 | Evan Swenson (10) | Loyola Academy | Wilmette | IL |
| 40 | :23.43 | Caroline Thomas (12) | DuPont Manual High School | Louisville | KY |
| 43 | :23.44 | Heather Arseth (12) | Wayzata High School | Plymouth | MN |
| 43 | :23.44 | Kathryn Eckhart (11) | Cy Creek High School | Houston | TX |
| 45 | :23.45 | Silken Jones (12) | San Clemente High School | San Clemente | CA |
| 45 | :23.45 | Linnea Mack (10) | Pioneer High School | San Jose | CA |
| 45 | :23.45 | Caroline Piehl (12) | Smoky Hill High School | Aurora | CO |
| 48 | :23.46 | Riki Bonnema (11) | Olympia High School | Orlando | FL |
| 49 | :23.47 | Jamie Friderichs (11) | Kingwood High School | Kingwood | TX |
| 50 | :23.48 | Kayla Hammerberg (12) | Upper Arlington High School | Upper Arlington | OH |
| 50 | :23.48 | Zoe Mattingly (11) | Zionsville Community High School | Zionsville | IN |
| 50 | :23.48 | Jordan Moxley (12) | Cortland Maplewood High School | Cortland | OH |
| 53 | :23.49 | Jayme Groth (12) | Bloomfield Hills Andover | Bloomfield Hills | MI |
| 53 | :23.49 | Tori Larsen (12) | York Community High School | Elmhurst | IL |
| 55 | :23.50 | Kate Bassett (12) | St. Catherine's School | Richmond | VA |
| 55 | :23.50 | Andrea Grant (12) | Walnut High School | Walnut | CA |
| 55 | :23.50 | Katie Kinnear (11) | Skyline High School | Sammamish | WA |
| 55 | :23.50 | Arden Pitman (12) | The Baylor School | Chattanooga | TN |
| 59 | :23.53 | Rachel Moore (11) | Andover High School | Andover | MA |
| 59 | :23.53 | Aja Vanhout (12) | Madison East High School | Madison | WI |
| 59 | :23.53 | Katherine Zander (12) | Orange Park High School | Orange Park | FL |
| 62 | :23.54 | Dana Holt (12) | Campolindo High School | Moraga | CA |
| 63 | :23.56 | Katherine Huff (11) | Lakeside High School | Evans | GA |
| 63 | :23.56 | Jordan Mattern (12) | Cherry Creek High School | Greenwood Village | CO |
| 63 | :23.56 | Elizabeth McGinn (12) | Millard West High School | Omaha | NE |
| 63 | :23.56 | Annie Tamblyn (11) | Ann Arbor Huron High School | Ann Arbor | MI |
| 67 | :23.57 | Amber Cratsenberg (11) | Thomas Jefferson High School | Auburn | WA |
| 67 | :23.57 | Carly Reid (9 ) | Monta Vista High School | Cupertino | CA |
| 69 | :23.58 | Megan Fonteno (12) | The Bolles School | Jacksonville | FL |
| 70 | :23.59 | Savannah Miller (11) | Westlake High School | Westlake Village | CA |
| 70 | :23.59 | Abi Speers (10) | Langley High School | McLean | VA |
| 72 | :23.60 | Macie McNichols (9 ) | Gilmour Academy | Gates Mills | OH |
| 73 | :23.61 | Ariana Bullard (10) | Carmel High School | Carmel | IN |
| 74 | :23.62 | Justine Panian (11) | Mission Hills High School | San Marcos | CA |
| 75 | :23.63 | Kathryn Ford (9 ) | Mt. Lebanon High School | Pittsburgh | PA |
| 76 | :23.64 | Katelyn Miller (12) | Hershey High School | Hershey | PA |
| 77 | :23.65 | Rebekah Land (12) | Hannibal High School | Hannibal | MO |
| 77 | :23.65 | Michele Rielly (11) | Bishop Watterson High School | Columbus | OH |
| 79 | :23.66 | Anika Apostalon (10) | Albuquerque Academy | Albuquerque | NM |
| 79 | :23.66 | Marissa Konicke (12) | Plano Senior High School | Plano | TX |
| 79 | :23.66 | Emily Neubert (12) | Midway High School | Waco | TX |
| 79 | :23.66 | Natalie Rohr (11) | Kettering Fairmont High School | Kettering | OH |
| 79 | :23.66 | Taylor Steffl (12) | Mercy High School | Farmington Hills | MI |
| 79 | :23.66 | Rhianna Williams (10) | Fossil Ridge High School | Fort Collins | CO |
| 79 | :23.66 | Kina Zhou (10) | Niskayuna High School | Niskayuna | NY |
| 86 | :23.67 | Hannah Raspopovich (11) | Crown Point High School | Crown Point | IN |
| 87 | :23.68 | Britta Sortland (12) | Woodbury High School | Woodbury | MN |
| 88 | :23.69 | Emily Baturka (11) | Episcopal Academy | Newtown Square | PA |
| 88 | :23.69 | Sarah Love (10) | DuPont Manual High School | Louisville | KY |
| 90 | :23.70 | Olivia Boggs (12) | Woodward Academy | College Park | GA |
| 90 | :23.70 | Haley Ferrer (12) | Academy Of Our Lady Of Peace | San Diego | CA |
| 90 | :23.70 | Alyssa Ruffing (9 ) | Franklin Regional High School | Murrysville | PA |
| 93 | :23.71 | Olivia Carter (11) | Astronaut High School | Titusville | FL |
| 94 | :23.72 | Margaret Burton (10) | University High School | Irvine | CA |
| 95 | :23.73 | Meredith Nakano (12) | Marist School | Atlanta | GA |
| 95 | :23.73 | Amy Novak (10) | Naperville North High School | Naperville | IL |
| 97 | :23.74 | Emily Cameron (10) | Warwick High School | Lititz | PA |
| 97 | :23.74 | Nancy Larson (12) | Mount Tabor High School | Winston-Salem | NC |
| 97 | :23.74 | Alexandra Marshall (10) | Ronald Wilson Reagan High School | Pfafftown | NC |
| 97 | :23.74 | Madison Peters (12) | Greater Atlanta Christian School | Norcross | GA |
| 97 | :23.74 | Amy Zhao (9 ) | Phillips Academy | Andover | MA |