| Place | Time | Relay Swimmers (Yrs) | School | City | State |
| 1 | 1:28.02 | Ryan Murphy (12), Joseph Schooling (11), Josh Booth (11), Santo Condorelli (12) | The Bolles School | Jacksonville | FL |
| 2 | 1:30.01 | David Boland (12), Joshua Ehrman (12), Michael Bundas (12), Adam Whitener (12) | Saline Area Schools | Saline | MI |
| 3 | 1:30.52 | Sven Campbell (12), Steven Stumph (12), J D Ratchford (12), Grant Sivesind (11) | Campolindo High School | Moraga | CA |
| 4 | 1:30.53 | Daryl Turner (12), John Matterm (12), Jake Markham (11), Eric Fuqua (11) | Cherry Creek High School | Englewood | CO |
| 5 | 1:31.16 | Sam Jo (9 ), Peter Kropp (12), Oliver Maarse (11), Corey John (11) | Loyola High School | Los Angeles | CA |
| 6 | 1:31.22 | Trent Trump (11), Nick Silverthorn (11), Maxime Rooney (9 ), Bryce McLaggan (11) | Granada High School | Livermore | CA |
| 7 | 1:31.28 | Robert Bantley (12), Cooper Tollen (11), Michael Jensen (9 ), Eric Jensen (12) | Upper Dublin High School | Fort Washington | PA |
| 8 | 1:31.51 | Joe Maginnis (12), Mike McBryan (11), Sean Regan (12), Greg Rogers (12) | LaSalle College High School | Wyndmoor | PA |
| 9 | 1:31.97 | Peter Simcox (11), Derek Hren (12), Nathan Christian (11), Charlie Pophal (12) | Saint Ignatius High School | Cleveland | OH |
| 10 | 1:32.00 | Christian Garkani (12), Tyler Lin (10), Justin Hanson (10), Blake Motal (12) | Corona del Mar High School | Newport Beach | CA |
| 11 | 1:32.06 | Matt Webster (12), Tim Kou (11), Chris Scheaffer (12), Cooper Burrill (10) | Bellarmine College Preparatory | San Jose | CA |
| 12 | 1:32.09 | Jack Mangan (12), Jae Park (11), Brian Walsh (12), David Schriesheim (12) | New Trier High School | Winnetka | IL |
| 13 | 1:32.12 | Benjamin Ho (9 ), Curtis Ogren (11), Taylor Ford (12), Sean Elmurib (10) | Saint Francis High School | Mountain View | CA |
| 14 | 1:32.13 | Clark Smith (12), Quinlan Stuart (10), Erik Biernat (12), Zach Suter (12) | Regis Jesuit High School | Aurora | CO |
| 15 | 1:32.18 | Aaron Greenberg (12), Griffin Back (9 ), Bryce Boston (12), Mike Solfelt (12) | Eden Prairie High School | Eden Prairie | MN |
| 16 | 1:32.22 | Ted Curtiss (12), Alex Goss (12), Reece Boyd (12), Grant Stafford (12) | Ravenwood High School | Brentwood | TN |
| 17 | 1:32.41 | Cannon Clifton (12), Ryan Sorensen (10), Dusan Vukobrat (12), John Sanden (11) | The Woodlands High School | The Woodlands | TX |
| 18 | 1:32.45 | Andy Hurst (11), Jack Wallar (11), Aaron Whitaker (11), Blake Pieroni (11) | Chesterton High School | Chesterton | IN |
| 19 | 1:32.56 | Albert Miao (12), Charlie Wiser (12), Jason Lammert (12), Gabe Ostler (11) | Miramonte High School | Orinda | CA |
| 20 | 1:32.68 | Brady Welch (11), Leo Mercer (12), Jack Conger (12), Matt Colket (12) | Our Lady of Good Counsel | Olney | MD |
| 21 | 1:32.75 | Jacob Molacek (11), Szymon Day (12), Ryan Tate (10), Sean Tate (10) | Creighton Preparatory School | Omaha | NE |
| 22 | 1:32.79 | Christian Sobczak (10), John Barone (11), Jonathon DiSalle (11), Nicholas Brodie (11) | St. Francis DeSales High School | Toledo | OH |
| 23 | 1:32.86 | Will Leach (12), Eddie Mapel (12), Brian Portland (10), Connor Schroyer (12) | Hinsdale Central High School | Hinsdale | IL |
| 24 | 1:32.93 | Taylor Dale (12), Pierson Scarborough (12), Ethan Young (9 ), Taylor Mathis (11) | Dalton High School | Dalton | GA |
| 25 | 1:32.97 | Anthoney Tsou (12), Zachary Yong (12), Corey Okubo (11), Michael Schiffer (11) | University High School | Irvine | CA |
| 26 | 1:33.01 | Luke Kaliszak (11), Dustin Tynes (11), Sam McHugh (11), Will Raines (10) | The Baylor School | Chattanooga | TN |
| 27 | 1:33.26 | Robert Leasure (12), Nicholas Sehlinger (12), William Harrison (11), Garrett Stephens (12) | Saint Xavier High School | Louisville | KY |
| 28 | 1:33.30 | Jonathan Roberts (11), John Remetta (12), Jacob Tovey (12), Jacob Eieson (12) | Southlake Carroll High School | Southlake | TX |
| 29 | 1:33.31 | Robert Glover (12), Neil Girmus (12), Jacob Malashock (10), Jim Glover (11) | Millard South High School | Omaha | NE |
| 29 | 1:33.31 | Thomas Trace (11), Ian Reardon (12), Maximilian Jelen (12), Joey Long (12) | Upper Arlington High School | Upper Arlington | OH |
| 31 | 1:33.33 | Daniel Smith (10), Bogdan Balteanu (12), Peter Grumhaus (12), Colin Rowe (12) | Lake Forest High School | Lake Forest | IL |
| 32 | 1:33.34 | Mate Kovacs (10), Tanner Anderson (12), Bowen Anderson (10), Seamus Lucero-Dixon (12) | Penn High School | Mishawaka | IN |
| 33 | 1:33.66 | Austin Doss (11), Zach Ceneviva (12), Shota Nakano (12), Jeremy Bauchwitz (12) | Hershey High School | Hershey | PA |
| 34 | 1:33.80 | Nick Johnston (12), Jason Chen (12), Bryan Hughes (12), Kevin McLaughlin (11) | Amador Valley High School | Pleasanton | CA |
| 34 | 1:33.80 | Luke Thorsell (10), Reese Frerichs (12), Andrew Seliskar (10), Miles Oakley (11) | Thomas Jefferson High School For Science And Tech | Alexandria | VA |
| 36 | 1:33.84 | Alex Snarski (11), Atticus Rush (11), Matthew Harrington (10), Justin Fu (10) | Libertyville High School | Libertyville | IL |
| 36 | 1:33.84 | Zachary Buerger (11), Casey Melzer (10), Greg Arnold (10), Max Staresinic (10) | North Allegheny Senior High School | Wexford | PA |
| 38 | 1:33.85 | Quinn Smith (11), Benjamin Wood (12), Miles Smachlo (9 ), Oscar Miao (12) | Deerfield Academy | Deerfield | MA |
| 39 | 1:33.89 | Ryan Ball (11), Nick Hatananka (12), Pat Jones (12), Ethan McNally (12) | Loveland High School | Loveland | CO |
| 40 | 1:33.93 | Vincent Carag (10), Jules Lawrence (12), Kyle Hendricks (11), Jacob Gonzales (12) | Klein Collins High School | Spring | TX |
| 41 | 1:34.06 | Alexander Lewis (11), Iain Edmundson (10), Julian Fraser (11), Edward Moss (10) | Greenwich High School | Greenwich | CT |
| 42 | 1:34.11 | Joseph Young (10), Jackson Russell (11), Rick Kelley (12), Noah Brenner (11) | Hamilton Southeastern High School | Fishers | IN |
| 42 | 1:34.11 | Ian Wooley (12), Steve Russo (12), James DelGado (12), Grant Carr (10) | Saint Xavier High School | Cincinnati | OH |
| 44 | 1:34.17 | Jared Smith (11), Gunner Braden (12), Jeremy Estes (12), Tore Grasso (12) | Boulder City High School | Boulder City | NV |
| 45 | 1:34.22 | Riley Hickman (10), Jonathan Pun (11), Matt Whittle (11), Sean Li (9 ) | Davis Senior High School | Davis | CA |
| 46 | 1:34.23 | Jake Precious (10), Todd Owen (11), Aaron Sexton (12), Branson Smith (10) | Ballard High School | Louisville | KY |
| 47 | 1:34.38 | Daniel Bridgers (12), Zach Marshall (11), Zach Bunner (12), Jimmy Yoder (12) | Lassiter High School | Marietta | GA |
| 48 | 1:34.39 | Austin Stepella (12), David Chokran (12), Nick Kowaleski (12), Kyle Gannon (12) | St. Charles North High School | St. Charles | IL |
| 49 | 1:34.42 | John Ferrara (12), Nick Arakelian (11), Bradley Bielicki (11), Jacob Goeddeke (11) | Stevenson High School | Livonia | MI |
| 50 | 1:34.43 | Matt Nephew (12), Jack Ryan (12), Max Irwin (12), Jack Spore (12) | Bloomington High School North | Bloomington | IN |
| 51 | 1:34.44 | Austin Flager (12), Jonathan Stoller (11), Austin Bernth (12), Takoda Friesen (11) | Northridge High School | Middlebury | IN |
| 51 | 1:34.44 | Kyle Patnode (12), Nathan Pimentel (12), Nikita Bondarenko (12), Mark Hallman (11) | Oak Park and River Forest High School | Oak Park | IL |
| 51 | 1:34.44 | Ryan Carson (12), Chris Guo (10), Grant Pinchot (10), Patrick Tippen (11) | Solon High School | Solon | OH |
| 54 | 1:34.47 | Daniel McArthur (10), Timothy Valdez (10), Nick Bustamante (10), Bryan Seel (12) | Lakewood High School | Lakewood | CA |
| 54 | 1:34.47 | Shea Ransford (12), Matt Tanchick (12), Brett Eslinger (11), Patrick Ransford (11) | Pittsford Central School | Pittsford | NY |
| 56 | 1:34.49 | Adam Stacklin (12), Stephen Ernst (12), Kelvin Newton (12), Mike McWhirter (12) | Waubonsie Valley High School | Aurora | IL |
| 57 | 1:34.51 | Mark Blinstrub (10), Andrew Grady (9 ), Nikolaus Lehnertz (12), Gust Kouvaris (10) | Brother Rice High School | Bloomfield Hills | MI |
| 58 | 1:34.52 | Brandon James (11), Daniel Comforti (10), Walker Thaning (11), Ryan Barsanti (12) | Heritage High School | Brentwood | CA |
| 58 | 1:34.52 | David Puczkowski (10), Ryan Lee (11), Yu-Bin Kim (11), Juson Hoo (12) | Westlake High School | Westlake Village | CA |
| 60 | 1:34.58 | Tim Wynter (11), Aaron Teo (10), Joe Faller (11), Scott Simpson (11) | Phillips Academy | Andover | MA |
| 60 | 1:34.58 | Ryan Freedman (11), Mitch Gartland (11), Eli Avart (10), Trip Caulfield (12) | Radnor High School | Wayne | PA |
| 62 | 1:34.60 | Alejandro Vassallo (11), Steven Vergona (12), Kevin Matheus (12), Sam Corona (12) | Boca Raton High School | Boca Raton | FL |
| 63 | 1:34.61 | William Steele (10), Pierce Bartine (12), Charles Steele (10), Andrew Steele (12) | Seven Lakes High School | Katy | TX |
| 64 | 1:34.63 | Max Williamson (12), Chase Vennefron (11), Robbie Newman (10), Brendan Meyer (9 ) | Covington Catholic High School | Park Hills | KY |
| 65 | 1:34.66 | Evan Pinion (12), Bryar Long (9 ), Ryan Burcham (11), Will Kerr (10) | Bearden High School | Knoxville | TN |
| 66 | 1:34.68 | Robert Whitacre (11), Alex D'Anna (11), Dean Shafritz (11), Ryan Josh Berger (12) | Christian Brothers Academy | Lincroft | NJ |
| 67 | 1:34.69 | Michael Palmer (12), Hank Poppe (9 ), Cody Tanabe (12), Nick Pasichuke (12) | San Ramon Valley High School | Danville | CA |
| 67 | 1:34.69 | Zach Switzer (12), Mac Trainor (12), Bear Bondurant (12), Alex Hapgood (12) | Woodberry Forest School | Woodberry Forest | VA |
| 69 | 1:34.70 | Timothy Martin (11), Evan Shive (10), Karol Schmuck (11), Josh Phelps (12) | Jeffersonville High School | Jeffersonville | IN |
| 70 | 1:34.75 | Brandon Goldstein (10), Carsten Vissering (10), Kevin Berry (9 ), Adrian Lin (10) | Georgetown Preparatory School | Rockville | MD |
| 71 | 1:34.76 | Edward Stolarski (10), John Hoin (11), Bryce Keblish (10), Bjorn Davis (11) | Fairfield College Preparatory School | Fairfield | CT |
| 71 | 1:34.76 | Dillon Williams (12), Noah Sol (9 ), Adam Pendergraft (12), Sean Bloore (11) | Monte Vista High School | Danville | CA |
| 73 | 1:34.77 | Jonathan DesCombes (12), Slater Goodman (12), Matthew Chalcarz (11), Spencer DeShon (12) | Capistrano Valley High School | Mission Viejo | CA |
| 74 | 1:34.78 | Craig Wasberg (11), David Newberger (10), Timmer Hoffmeister (10), Nick Willison (12) | Rockford High School | Rockford | MI |
| 75 | 1:34.80 | Drew Biro (12), Kevin Bressler (12), Michael Kessler (12), Sean Mulvin (10) | Perkins High School | Sandusky | OH |
| 76 | 1:34.81 | Connor Bos (12), Kyle Doss (12), Gage Mitchell (12), Jonathon Maat (12) | Holland High School | Holland | MI |
| 77 | 1:34.82 | Doni Moffa (11), Ross Palazzo (10), Brendon Mulcahey (10), Ryan Hutcheson (12) | Hudson High School | Hudson | OH |
| 77 | 1:34.82 | C J Schaffer (11), Paul Stockett (12), Christopher Cary (11), Erik Dresden (11) | Malvern Preparatory School | Malvern | PA |
| 79 | 1:34.83 | Matthew Erickson (11), Chris Klein (12), Kai Williams (10), Thad Stalmack (11) | Ann Arbor Pioneer High School | Ann Arbor | MI |
| 80 | 1:34.85 | Todd Ber (9 ), Andrew Reynolds (12), Robert Slaughter (10), Marshall Pringle (12) | Klein High School | Klein | TX |
| 81 | 1:34.88 | Mike Burke (11), Josh Kanute (12), Robert Ramoska (12), Jack Fergus (11) | Marmion Academy | Aurora | IL |
| 82 | 1:34.95 | Matt Farmer Farmer (12), Tommy McGuire (12), Cavan Smith (9 ), Zach Tieke (11) | Fenwick High School | Oak Park | IL |
| 83 | 1:34.99 | Tad Spence (12), Ryan Cade (12), Chris Daniels (10), Seth Maslowski (10) | Green Hope High School | Cary | NC |
| 84 | 1:35.07 | Zach Miller (11), Rex Riley (9 ), Luke Merski (12), Mike Squeglia (12) | Cathedral Preparatory School | Erie | PA |
| 85 | 1:35.08 | Mason Acevedo (12), Jon Walters (12), James Walters (11), Dylan Payne (12) | Mater Dei High School | Santa Ana | CA |
| 85 | 1:35.08 | James Elmendorf (10), Alex Mesisca (12), Jon Burkett (10), Bryan Mattingly (11) | Shawnee High School | Medford | NJ |
| 87 | 1:35.09 | Max McKay (12), Derek Stauder (10), Mitch Cooper (11), Mark Ordway (12) | Carmel High School | Carmel | IN |
| 88 | 1:35.10 | Jack Lindell (12), Erick Huft (12), Brett Weicht (10), Pierce Schultz (12) | Edina High School | Edna | MN |
| 89 | 1:35.12 | Dominic Breschi (12), Kevin Blum (12), Thomas Brennan (12), Trey Perry (11) | Loyola Blakefield | Towson | MD |
| 90 | 1:35.13 | Jack Walsh (10), Ryan Newman (12), Christopher Vela (10), Timothy Szuba (12) | Detroit Catholic Central High School | Novi | MI |
| 91 | 1:35.17 | Jeremy Temprano (12), Henry Patterson (12), John Hornacek (11), Ben Immerfall (12) | James Madison Memorial High School | Madison | WI |
| 91 | 1:35.17 | Garrett Chin (11), Brandon Nguyen (12), Symeon Stefan (12), Peter Loakes (11) | La Canada High School | La Canada - Flintridge | CA |
| 91 | 1:35.17 | Alex O'Laughlin (12), Stanley Wu (10), Michal Zyla (11), Zach Loza (12) | Northgate High School | Walnut Creek | CA |
| 94 | 1:35.20 | Theodore Steinkamp (12), Sean Hayden (11), Rawley Davis (11), Samuel Lorentz (12) | North Central High School | Indianapolis | IN |
| 95 | 1:35.24 | Alex Walton (10), Michael Sovers (11), Travis Greenwald (12), Matt Krueger (12) | Muscatine High School | Muscatine | IA |
| 96 | 1:35.27 | Noah Busch (12), Chris Bader (12), Daniel Bielski (12), Ryan Jessen (11) | Minnetonka High School | Minnetonka | MN |
| 97 | 1:35.28 | Will Anderson (12), Jackson Algiers (10), Will Glass (12), Russell Noletto (10) | McGill-Toolen Catholic High School | Mobile | AL |
| 97 | 1:35.28 | Dan Pletz (12), Chris Buzard (12), Kyle Higgins (12), Sebastian Yocca (9 ) | Peters Township High School | McMurray | PA |
| 99 | 1:35.29 | Soren Evans (11), Matthew Ankerholz (12), Scott Goddin (12), Trevor Mylin (12) | Seminole High School | Sanford | FL |
| 100 | 1:35.31 | Declan Kennon (11), William Fierro Joyce (12), Oliver Patrouch (11), Michael Verini (10) | Fordham Preparatory School | Bronx | NY |