| Place | Time | Swimmer (Yr) | School | City | State |
| 1 | :21.98 | Abbey Weitzeil (11) | Saugus High School | Saugus | CA |
| 2 | :22.11 | Janet Hu (12) | Oakton High School | Vienna | VA |
| 3 | :22.15 | Amy Bilquist (11) | Carmel High School | Carmel | IN |
| 4 | :22.51 | Bethany Galat (12) | Penn High School | Mishawaka | IN |
| 5 | :22.66 | Kasey Schmidt (11) | The Bolles School | Jacksonville | FL |
| 5 | :22.66 | Mimi Schneider (12) | Fenwick High School | Oak Park | IL |
| 7 | :22.68 | Alex Cleveland (12) | Zionsville Community High School | Zionsville | IN |
| 8 | :22.69 | Caitlin Cooper (12) | Woodward Academy | College Park | GA |
| 9 | :22.71 | Kaitlyn Albertoli (11) | Jserra Catholic High School | San Juan Capistrano | CA |
| 9 | :22.71 | Lindsey Engel (12) | Crean Lutheran High School | Irvine | CA |
| 11 | :22.77 | Kathryn McLaughlin (11) | Santa Margarita Catholic High School | Rancho Santa Margarita | CA |
| 12 | :22.80 | Lexie Lupton (11) | Kingwood High School | Kingwood | TX |
| 13 | :22.81 | Rachel Wittmer (9 ) | Edina High School | Edina | MN |
| 14 | :22.87 | Danielle Nack (12) | Mankato West High School | Mankato | MN |
| 15 | :22.88 | Nora McCullagh (11) | Charlotte Catholic High School | Charlotte | NC |
| 16 | :22.91 | Veronica Burchill (10) | Carmel High School | Carmel | IN |
| 17 | :22.95 | Emily Murphy (12) | Lima Shawnee High School | Lima | OH |
| 18 | :22.96 | Kenna Ramey (12) | Federal Way High Schoolf | Federal Way | WA |
| 19 | :22.97 | Morgan Hill (10) | Sherwood High School | Sandy Spring | MD |
| 20 | :22.98 | Amy Lubawy (12) | Bishop Gorman High School | Las Vegas | NV |
| 21 | :23.00 | Caroline Baldwin (12) | Westfield High School | Westfield | NJ |
| 22 | :23.03 | Jasmine Mau (12) | Punahou School | Honolulu | HI |
| 23 | :23.04 | Grace Zhao (9 ) | Palo Alto High School | Palo Alto High School | CA |
| 24 | :23.05 | Emily Allen (11) | William A. Hough High School | Cornelius | NC |
| 24 | :23.05 | Vanessa Krause (10) | Chesterton High School | Chesterton | IN |
| 24 | :23.05 | Katie Smith (10) | Pittsford Central Schools | Pittsford | NY |
| 27 | :23.07 | Ally Howe (12) | Sacred Heart Preparatory | Atherton | CA |
| 27 | :23.07 | GraceAnne Long (11) | Upper Arlington High School | Upper Arlington | OH |
| 29 | :23.10 | Marta Ciesla (9 ) | Pine Crest School | Fort Lauderdale | FL |
| 29 | :23.10 | Jamie Stone (9 ) | Centennial High School | Gresham | OR |
| 31 | :23.11 | Annie Ochitwa (11) | Thunderridge High School | Highlands Ranch | CO |
| 32 | :23.12 | Victoria Toris (11) | Pinnacle High School | Phoenix | AZ |
| 33 | :23.13 | Rachel Hayden (12) | North Central High School | Indianapolis | IN |
| 33 | :23.13 | Dina Rommel (12) | Clarence High School | Clarence | NY |
| 33 | :23.13 | Madelyn Veith (12) | Hershey High School | Hershey | PA |
| 36 | :23.14 | Brooke Bauer (10) | Sacred Heart Academy | Louisville | KY |
| 36 | :23.14 | Macie McNichols (12) | Gilmour Academy | Gates Mills | OH |
| 38 | :23.16 | Katie Ford (12) | Mt. Lebanon High School | Pittsburgh | PA |
| 39 | :23.18 | Raena Eldridge (11) | Rockwall High School | Rockwall | TX |
| 39 | :23.18 | Daria Pyshnenko (9 ) | Lake Forest High School | Lake Forest | IL |
| 41 | :23.20 | Anna Keane (12) | Meadowdale High School | Lynnwood | WA |
| 42 | :23.21 | Valerie Hull (12) | Westview High School | San Diego | CA |
| 43 | :23.23 | Breonna Barker (11) | Broken Arrow High School | Broken Arrow | OK |
| 43 | :23.23 | Caroline McTaggart (11) | The Holton Arms School | Bethesda | MD |
| 45 | :23.26 | Clara Baggett (11) | Mt. Vernon High School | Mt. Vernon | IN |
| 45 | :23.26 | Wheeler Jordan (10) | Atascocita High School | Humble | TX |
| 45 | :23.26 | Lauren Moden (11) | Legend High School | Parker | CO |
| 45 | :23.26 | Ingrid Wall (9 ) | New Trier High School | Winnetka | IL |
| 45 | :23.26 | Katie Wells (11) | Glenbrook South High School | Glenview | IL |
| 50 | :23.28 | Iris Brand (11) | Amador Valley High School | Pleasanton | CA |
| 50 | :23.28 | Tamara Santoyo (11) | William S. Hart High School | Newhall | CA |
| 50 | :23.28 | Ashley Volpenhein (9 ) | Mason High School | Mason | OH |
| 53 | :23.29 | Erin Falconer (11) | Mundelein High School | Mundelein | IL |
| 53 | :23.29 | Mary Warren (12) | Arrowhead High School | Hartland | WI |
| 55 | :23.30 | Ashton Ellzey (12) | Baker High School | Mobile | AL |
| 55 | :23.30 | Grace Oglesby (10) | North Oldham High School | Goshen | KY |
| 57 | :23.31 | Maddy Burnham (12) | Bettendorf High School | Bettendorf | IA |
| 57 | :23.31 | Aja Grande (12) | Iolani School | Honolulu | HI |
| 59 | :23.33 | Hannah Baker (10) | Robinson Secondary School | Fairfax | VA |
| 60 | :23.35 | Sarah Kaunitz (12) | Monta Vista High School | Cupertino | CA |
| 61 | :23.36 | Holly Christensen (11) | Hunterdon Central High School | Flemington | NJ |
| 61 | :23.36 | Robyn Clevenger (10) | Hamilton Southeastern High School | Fishers | IN |
| 61 | :23.36 | Kaia Grobe (11) | Chanhassen High School | Chanhassen | MN |
| 61 | :23.36 | Courtney Kresl (10) | Carroll High School | Fort Wayne | IN |
| 65 | :23.37 | Anelise Diener (11) | Alamo Heights High School | San Antonio, Texas | TX |
| 65 | :23.37 | Colleen Donlin (10) | Wayzata High School | Plymouth | MN |
| 65 | :23.37 | Cheyenne Meek (12) | Port Clinton High School | Port Clinton | OH |
| 68 | :23.38 | Abigail Kochevar (10) | Rock Canyon High School | Highlands Ranch | CO |
| 68 | :23.38 | Laura Miksch (12) | Columbus High School | Columbus | NE |
| 68 | :23.38 | Amy Okada (10) | Beverly Hills High School | Beverly Hills | CA |
| 71 | :23.39 | Abbie Dolan (10) | Visitation High School | Mendota Heights | MN |
| 71 | :23.39 | Heidi Poppe (12) | San Ramon Valley High School | Danville | CA |
| 71 | :23.39 | Carly Reid (12) | Monta Vista High School | Cupertino | CA |
| 74 | :23.40 | Claire Adams (10) | Carmel High School | Carmel | IN |
| 74 | :23.40 | Samantha Fazio (11) | Pinnacle High School | Phoenix | AZ |
| 74 | :23.40 | Lauren E. Heller (10) | Walsh Jesuit High School | Cuyahoga Falls | OH |
| 74 | :23.40 | Hannah Stevens (12) | Lexington High School | Lexington | OH |
| 78 | :23.42 | Miranda Donley (9 ) | Columbus School For Girls | Columbus | OH |
| 78 | :23.42 | Alexandria Hubel (11) | Boulder City High School | Boulder City | NV |
| 80 | :23.44 | Kate Boyer (11) | Highland Park High School | Dallas | TX |
| 80 | :23.44 | Amy Zhao (12) | Phillips Academy | Andover | MA |
| 82 | :23.45 | Olivia Calegan (9 ) | Lincoln Southwest High School | Lincoln | NE |
| 82 | :23.45 | Breanna Roman (12) | The Baylor School | Chattanooga | TN |
| 84 | :23.46 | Emma Cottrill (9 ) | The Athenian School | Danville | CA |
| 84 | :23.46 | Logan Graumann (12) | Maryville High School | Maryville | TN |
| 84 | :23.46 | Solveig Viren (12) | Grand Rapids High School | Grand Rapids | MN |
| 87 | :23.47 | Mary Beth Blocher (12) | Munster High School | Munster | IN |
| 87 | :23.47 | Maddie Gehrke (11) | Waukee High School | Waukee | IA |
| 87 | :23.47 | Claire Mikesell (10) | Clearfield High School | Clearfield | PA |
| 90 | :23.48 | Rachel Grooms (12) | Seven Lakes High School | Katy | TX |
| 91 | :23.49 | Kelly Jacob (10) | Arrowhead High School | Hartland | WI |
| 91 | :23.49 | Alexandra Rockett (12) | Wilson High School | West Lawn | PA |
| 93 | :23.53 | Cecelia Williams (12) | Lawton Chiles High School | Tallahassee | FL |
| 93 | :23.53 | Emma Wittmer (11) | Edina High School | Edina | MN |
| 95 | :23.54 | Noel Styer (12) | Ocean City High School | Ocean City | NJ |
| 96 | :23.55 | Elise Haan (11) | Gulf Coast High School | Naples | FL |
| 97 | :23.56 | Jinan Andrews (12) | Vernon Township High School | Vernon | NJ |
| 97 | :23.56 | Siobhan Dale (11) | Edwin O. Smith High School | Storrs | CT |
| 97 | :23.56 | Leila Johnston (11) | Mount Desert Island High School | Bar Harbor | ME |
| 100 | :23.57 | Brie Balsbough (12) | West Linn High School | West Linn | OR |
| 100 | :23.57 | Roxy Griffore (11) | Mercy High School | Farmington Hills | MI |
| 100 | :23.57 | Hannah Whiteley (10) | Springboro High School | Springboro | OH |