| Place | Time | Name (Grade) | School | City | State |
| 1 | :48.33 | Dagny Knutson (11) | Minot High School | Minot | ND |
| 2 | :48.53 | Samantha Tucker (11) | Westlake High School | Austin | TX |
| 3 | :48.98 | Jasmine Tosky (9 ) | Palo Alto High School | Palo Alto | CA |
| 4 | :48.99 | Margo Geer (11) | Fairbanks High School | Milford Center | OH |
| 5 | :49.15 | Rebecca Jones (12) | First Colonial High School | Virginia Beach | VA |
| 6 | :49.24 | Jamie Bohunicky (12) | Buchholz High School | Gainesville | FL |
| 7 | :49.34 | Maddy Schaefer (10) | Saint Francis High School | Mountain View | CA |
| 8 | :49.45 | Kasey Carlson (11) | Las Lomas High School | Walnut Creek | CA |
| 9 | :49.53 | Megan Romano (12) | Northeast High School | St Petersburg | FL |
| 10 | :49.59 | Mary Beck (12) | Westlake High School | Austin | TX |
| 11 | :49.63 | Andrea Murez (12) | Venice Senior High School | Los Angeles | CA |
| 12 | :49.64 | Haley Krakoski (11) | Xavier College Preparatory | Phoenix | AZ |
| 13 | :49.67 | Gracie Finnegan (11) | Bishop Watterson High School | Columbus | OH |
| 14 | :49.75 | Katie Nolan (12) | Hershey High School | Hershey | PA |
| 15 | :49.78 | Hannah Bowen (10) | Stillwater High School | Stillwater | MN |
| 16 | :49.80 | Meredith Cavalier (12) | Brooke Point High School | Stafford | VA |
| 16 | :49.80 | Lauren Perdue (12) | J. H. Rose High School | Greenville | NC |
| 18 | :49.81 | Gretchen Jaques (10) | Glendora High School | Glendora | CA |
| 19 | :49.82 | Chelsea Bailey (10) | Kentlake High School | Kent | WA |
| 20 | :49.89 | Cynthia Fascella (11) | Fountain Valley High School | Fountain Valley | CA |
| 21 | :49.97 | Stephanie Eisenring (12) | Pine Crest School | Fort Lauderdale | FL |
| 21 | :49.97 | Andie Taylor (11) | Skyline High School | Sammamish | WA |
| 23 | :49.99 | Maya DiRado (11) | Maria Carrillo High School | Santa Rosa | CA |
| 24 | :50.02 | Tiffany Van Dongen (12) | Klein Collins High School | Spring | TX |
| 25 | :50.09 | Ruby Martin (12) | Madison East High School | Madison | WI |
| 26 | :50.12 | Kathryn Murphy (11) | Marin Catholic High School | Kentfield | CA |
| 27 | :50.15 | Caroline Kenney (11) | North Gwinnett High School | Suwanee | GA |
| 28 | :50.24 | Carly Mercer (11) | Hamilton Southeastern High School | Fishers | IN |
| 29 | :50.26 | Krissie Brandenburg (11) | Beechwood High School | Fort Mitchell | KY |
| 30 | :50.27 | Anna Dobben (12) | Homewood-Flossmoor High School | Flossmoor | IL |
| 31 | :50.29 | Kelsey Amundsen (12) | The Woodlands High School | The Woodlands | TX |
| 32 | :50.33 | Chelsea Fong (11) | Monta Vista High School | Cupertino | CA |
| 32 | :50.33 | Danielle Jansen (11) | Mason High School | Mason | OH |
| 34 | :50.38 | Kait Flederbach (11) | Westfield High School | Westfield | IN |
| 35 | :50.39 | Mary Hanson (11) | Immanuel Christian | Ridgecrest | CA |
| 36 | :50.40 | Megan Lydzinski (9 ) | Montgomery High School | Skillman | NJ |
| 37 | :50.44 | Jackie Powell (11) | Madison Memorial High School | Madison | WI |
| 38 | :50.47 | Emma Drysdale (12) | Monta Vista High School | Cupertino | CA |
| 39 | :50.49 | Aja Van Hout (10) | Madison East High School | Madison | WI |
| 40 | :50.57 | Megan Detro (12) | Carmel High School | Carmel | IN |
| 41 | :50.58 | Sloane Pitman (12) | The Baylor School | Chattanooga | TN |
| 42 | :50.59 | Emily Andelson (12) | Palm Desert High School | Palm Desert | CA |
| 42 | :50.59 | Catherine Breed (10) | Amador Valley High School | Pleasanton | CA |
| 44 | :50.61 | Carolyn Fittin (10) | Peddie School | Hightstown | NJ |
| 45 | :50.64 | Alexandra Whitford (11) | Bella Vista High School | Fair Oaks | CA |
| 46 | :50.65 | Katherine Carl (12) | Bloomfield Hills Lahser High School | Bloomfield Hills | MI |
| 46 | :50.65 | Abigail Staats (12) | Winona High School | Winona | MN |
| 48 | :50.68 | Lindsey Rae Marchand (12) | Peninsula High School | Gig Harbor | WA |
| 49 | :50.69 | Sara Delay (11) | Northgate High School | Walnut Creek | CA |
| 50 | :50.71 | Hanna Cowley (10) | Ann Arbor Pioneer High School | Ann Arbor | MI |
| 51 | :50.72 | Melanie Margalis (11) | Countryside High School | Clearwater | FL |
| 51 | :50.72 | Molly Osterhage (11) | Centerville High School | Centerville | OH |
| 53 | :50.78 | Zoe Mattingly (9 ) | Zionsville Community High School | Zionsville | IN |
| 53 | :50.78 | Allyson Sweeney (12) | Brookwood High School | Snellville | GA |
| 55 | :50.79 | Kelly Hagerty (11) | Glenbrook South High School | Glenview | IL |
| 55 | :50.79 | Patricia Leeson (11) | Liberty High School | Bethlehem | PA |
| 57 | :50.81 | Emily Bos (11) | Holland High School | Holland | MI |
| 58 | :50.82 | Mary Moser (11) | Wyomissing Area High School | Wyomissing | PA |
| 59 | :50.83 | Katie Stover (12) | Rocklin High School | Rocklin | CA |
| 59 | :50.83 | Katie Tomkinson (12) | Carlsbad High School | Carlsbad | CA |
| 61 | :50.84 | Katie Howard (11) | Sacred Heart Prepararory | Atherton | CA |
| 62 | :50.85 | Lauren Nichols (12) | Seaholm High School | Birmingham | MI |
| 62 | :50.85 | Kate Shumway (12) | New Trier High School | Winnetka | IL |
| 64 | :50.89 | Rachel Burns (12) | Countryside High School | Clearwater | FL |
| 64 | :50.89 | Emily Lloyd (11) | Severna Park High School | Severna Park | MD |
| 66 | :50.90 | Skylar Smith (10) | Foster High School | Richmond | TX |
| 67 | :50.91 | Trish Regan (11) | Carmel High School | Carmel | IN |
| 68 | :50.96 | Stacey Stanfield (9 ) | St. Augustine High School | St. Augustine | FL |
| 69 | :50.98 | Amanda Kendall (12) | Robinson Secondary School | Fairfax | VA |
| 69 | :50.98 | Aubrey Peacock (11) | The Bolles School | Jacksonville | FL |
| 71 | :51.01 | Sara Li (11) | Longmeadow High School | Longmeadow | MA |
| 71 | :51.01 | Lindsey Norberg (12) | Ithaca High School | Ithaca | NY |
| 73 | :51.02 | Andrea Grant (10) | Walnut High School | Walnut | CA |
| 74 | :51.03 | Dana Nessler (11) | The Bolles School | Jacksonville | FL |
| 75 | :51.04 | Allison Hendren (12) | Leesville Road High School | Raleigh | NC |
| 76 | :51.05 | Kate Klippert (11) | Newport Harbor High School | Newport Beach | CA |
| 76 | :51.05 | Danielle Siverling (10) | Downingtown East High School | Exton | PA |
| 78 | :51.06 | Margaret Anderson (12) | H.B. Plant High School | Tampa | FL |
| 79 | :51.08 | Katelin Scarsella (12) | Westlake High School | Austin | TX |
| 80 | :51.11 | Lara Moseley (12) | Pine Crest School | Fort Lauderdale | FL |
| 80 | :51.11 | Calley Parham (12) | Monterey High School | Lubbock | TX |
| 82 | :51.12 | Erin Caflisch (11) | Mayo High School | Rochester | MN |
| 83 | :51.14 | Logan Mason (12) | Carmel High School | Carmel | IN |
| 84 | :51.15 | Lauren Hines (12) | Hidden Valley High School | Roanoke | VA |
| 85 | :51.16 | Kristen Wilson (11) | Paul Laurence Dunbar High School | Lexington | KY |
| 86 | :51.17 | Meghan Weiss (12) | Visitation High School | Mendota Heights | MN |
| 87 | :51.18 | Hailey Campbell (11) | Lakeville South High School | Lakeville | MN |
| 87 | :51.18 | Jenna Gregoire (11) | Rampart High School | Colorado Springs | CO |
| 89 | :51.20 | Kim Pavlin (11) | Churchill High School | San Antonio | TX |
| 90 | :51.21 | Erin Foster (10) | The Woodlands High School | The Woodlands | TX |
| 91 | :51.22 | Samantha Bosma (10) | Lassiter High School | Marietta | GA |
| 92 | :51.23 | Shannon Landgrebe (12) | Palm Desert High School | Palm Desert | CA |
| 92 | :51.23 | Haley Pietila (9 ) | Arrowhead High School | Hartland | WI |
| 94 | :51.24 | Dani Barbiea (10) | Springboro High School | Springboro | OH |
| 94 | :51.24 | Alana Pazevic (11) | H. M. Jackson High School | Mill Creek | WA |
| 96 | :51.25 | Yumi So (12) | Crescenta Valley High School | La Crescenta | CA |
| 97 | :51.27 | Casey Clark (10) | Klein High School | Klein | TX |
| 97 | :51.27 | Maddy Dalcamo (11) | Olathe Northwest High School | Olathe | KS |
| 99 | :51.31 | Lauren Driscoll (9 ) | American Heritage School | Plantation | FL |
| 100 | :51.32 | Lily Moldenhauer (11) | Churchill High School | San Antonio | TX |
| 101 | :51.33 | Kaila Lee (11) | Willamette High School | Eugene | OR |
| 101 | :51.33 | Kayla Smith (12) | Madison Memorial High School | Madison | WI |
| 103 | :51.34 | Ginny Grams (10) | Spruce Creek High School | Port Orange | FL |
| 104 | :51.35 | Katelyne Herrington (11) | Tokay High School | Lodi | CA |
| 105 | :51.39 | Meagan Hairston (12) | Plano West Senior High School | Plano | TX |
| 106 | :51.40 | Samantha Moffitt (10) | Cedar Crest High School | Lebanon | PA |
| 107 | :51.41 | Evann Heidersbach (12) | Elyria Catholic High School | Elyria | OH |
| 106 | :51.41 | Shelby Webber (10) | Fountain Valley High School | Fountain Valley | CA |
| 109 | :51.42 | Gabrielle Mizerak (12) | Osbourn Park High School | Manassas | VA |
| 110 | :51.45 | Alexa Morris (10) | Ronald Reagan High School | San Antonio | TX |
| 111 | :51.47 | Wylie Escobedo (11) | Austin High School | Austin | TX |
| 111 | :51.47 | Kayla Hammerberg (10) | Upper Arlington High School | Upper Arlington | OH |
| 113 | :51.48 | Ashlee Linn (9 ) | Riverview High School | Sarasota | FL |
| 114 | :51.49 | Kristen Clarno (9 ) | Homestead High School | Cupertino | CA |
| 114 | :51.49 | Katherine Huff (9 ) | Lakeside High School | Evans | GA |
| 114 | :51.49 | Stephanie Kinsey (11) | Trinity High School | Camp Hill | PA |
| 117 | :51.50 | Katelyn Miller (10) | Hershey High School | Hershey | PA |
| 118 | :51.51 | Chardonnay Biter-Mundt (12) | Vintage High School | Napa | CA |
| 119 | :51.52 | Mary Griffith (9 ) | Tokay High School | Lodi | CA |
| 120 | :51.54 | Courtney Wilde (10) | Laguna Hills High School | Laguna Hills | CA |
| 121 | :51.55 | Nadia El-Hamdi (10) | James Bowie High School | Austin | TX |
| 121 | :51.55 | Christine Regone (12) | James E. Taylor High School | Katy | TX |
| 123 | :51.56 | Karen Wang (11) | Foothill High School | Pleasanton | CA |
| 124 | :51.57 | Deirdre Jones (12) | University School of Nashville | Nashville | TN |
| 125 | :51.58 | Kelsey Klatt (12) | Sunnyside High School | Fresno | CA |
| 126 | :51.59 | Jenny Darby (10) | Hardin Valley Academy | Knoxville | TN |
| 126 | :51.59 | Laura Evans (12) | Greenwich High School | Greenwich | CT |
| 128 | :51.60 | Adrienne Bicek (12) | Downers Grove North High School | Downers Grove | IL |
| 128 | :51.60 | Missy Doll (11) | Souderton Area High School | Souderton | PA |
| 128 | :51.60 | Maureen McLaine (12) | Plano West Senior High School | Plano | TX |
| 131 | :51.61 | Kara Stranski (11) | St. Mary's Academy | Portland | OR |
| 132 | :51.62 | Lynette Lim (11) | Palm Springs High School | Palm Springs | CA |
| 132 | :51.62 | TJ Padova (12) | Campbell County High School | Gillette | WY |
| 134 | :51.64 | Michelle Gean (11) | Kingwood High School | Kingwood | TX |
| 134 | :51.64 | Emma O'Connell (10) | Millard West High School | Omaha | NE |
| 136 | :51.65 | Claire Hunter (11) | Hackley School | Tarrytown | NY |
| 137 | :51.66 | Mikaela Macklin (11) | El Dorado High School | Placerville | CA |
| 138 | :51.67 | Stephanie Koch (12) | Ames High School | Ames | IA |
| 138 | :51.67 | Kelsie Schooley (12) | Holt High School | Holt | MI |
| 140 | :51.68 | Brooke Brull (12) | Shawnee Mission Northwest High School | Shawnee | KS |
| 140 | :51.68 | Mikelle Masciantonio (11) | Emmaus High School | Emmaus | PA |
| 142 | :51.69 | Bonnie Brandon (9 ) | Cherry Creek High School | Greenwood Village | CO |
| 142 | :51.69 | Paige Impink (11) | Wilson High School | West Lawn | PA |
| 144 | :51.70 | Shelley Perkins (12) | Chatfield Senior High School | Littleton | CO |
| 145 | :51.71 | Brooke Fuller (11) | Johansen High School | Modesto | CA |
| 146 | :51.72 | Caitlyn Karr (10) | Wilson High School | West Lawn | PA |
| 146 | :51.72 | Anna Labozan (10) | Monarch High School | Louisville | CO |
| 146 | :51.72 | Patricia Nelson (11) | Fort Collins High School | Fort Collins | CO |
| 146 | :51.72 | Emily Ryczek (10) | Sherwood High School | Sandy Spring | MD |